Impact of Plasma p‐tau181 on Cognition, Motor Phenotypes, and Disease Course in ALS
ABSTRACT Phosphorylated tau181 (p‐tau181), an Alzheimer's disease biomarker, was recently evaluated in amyotrophic lateral sclerosis (ALS). We investigated plasma p‐tau181 in 202 ALS/ALS‐FTD patients and 94 healthy controls, assessing cognitive performance, motor function, and longitudinal dynamics.
Elisabeth Kasper +25 more
wiley +1 more source
JAK-STAT and IL-17 pathway dysregulation underlies persistent immune dysfunction in ART-experienced people living with HIV in Ghana. [PDF]
Appeaning M +17 more
europepmc +1 more source
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension phase).
Fabrizio De Benedetti +19 more
wiley +1 more source
Serum levels of immunoglobulin G and M antibodies against SARS-CoV-2 in asymptomatic individuals prior to COVID-19 vaccination in the Democratic Republic of Congo. [PDF]
Mukenge EK +13 more
europepmc +1 more source
Gestational Diabetes and Long-Term Risk of Maternal Kidney Disease: Systematic Review and Meta-Analysis of Population Base Cohort Studies. [PDF]
Bahardoust M +7 more
europepmc +1 more source
Acellular dermal matrix alone or in combination with subacromial bursa and humeral bone marrow concentrate for augmentation of massive rotator cuff tear repair: a double-blind randomized controlled trial protocol (MODA). [PDF]
Cavallo M +8 more
europepmc +1 more source
Decoupled Climatic Drivers of Tree and Ground-Layer Carbon Uptake in Mountain Ecosystems Around the World. [PDF]
Mallen-Cooper M +18 more
europepmc +1 more source
Klotho levels and biological age acceleration: Insights from a diverse cohort of middle-aged and elderly individuals. [PDF]
Huang M +7 more
europepmc +1 more source
Vitamin D Deficiency in Institutionalized Older Adults: Associations with Supplementation Practices but Not with Cognitive Decline or Dementia. [PDF]
Soares LD +15 more
europepmc +1 more source

