Results 51 to 60 of about 3,716,507 (339)
Structure and parameter estimation for cell systems biology models [PDF]
, 2008 In this work we present a new methodology for structure and parameter estimation in cell systems biology modelling. Our modelling framework is based on P systems, an unconventional computational paradigm that abstracts from the structure and functioning ...
Cao, Hongqing +3 more
core
Summary statement of the Asilomar conference on recombinant DNA molecules [PDF]
, 1975 This meeting was organized to review scientific progress in research on recombinant DNA molecules and to discuss appropriate ways to deal with the potential biohazards of this work.
Baltimore, David +4 more
core +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Visualization of PS/γ-Secretase Activity in Living Cells
iScience, 2020 Summary: A change in Presenilin (PS)/γ-secretase activity is linked to essential biological events as well as to the progression of many diseases. However, not much is known about how PS/γ-secretase activity is spatiotemporally regulated in cells. One of
Masato Maesako +5 more
doaj
Machine Learning for Uncovering Biological Insights in Spatial Transcriptomics Data [PDF]
arXiv, 2023 Development and homeostasis in multicellular systems both require exquisite control over spatial molecular pattern formation and maintenance. Advances in spatially-resolved and high-throughput molecular imaging methods such as multiplexed immunofluorescence and spatial transcriptomics (ST) provide exciting new opportunities to augment our fundamental ...
arxiv
TEACHING METHODOLOGY OF BIOLOGICAL SCIENCE IN SCHOOLS
Teaching methodology in biological science plays a crucial role in shaping students' understanding and interest in the subject. This article explores various innovative teaching methods and strategies that can be employed in schools to enhance the learning experience and promote a deeper understanding of biological concepts. It discusses the importance
Abatova Feruza Reymbaevn +2 more
openaire +1 more source
Detection of Epigenomic Network Community Oncomarkers [PDF]
, 2016 In this paper we propose network methodology to infer prognostic cancer biomarkers based on the epigenetic pattern DNA methylation. Epigenetic processes such as DNA methylation reflect environmental risk factors, and are increasingly recognised for their
Bartlett, Thomas E., Zaikin, Alexey
core +2 more sources
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
Behavioral variation across the days and lives of honey bees
iScience, 2022 Summary: In honey bee colonies, workers generally change tasks with age (from brood care, to nest work, to foraging). While these trends are well established, our understanding of how individuals distribute tasks during a day, and how individuals differ ...
Michael L. Smith +5 more
doaj
Multiple Shoots Induction from Indigenous Nigerian Pumpkin (Cucurbita pepo L.) [PDF]
, 2017 Aim: The aim of this study is to develop a protocol for in vitro regeneration of a Nigerian indigenous pumpkin (C. pepo L.) via seedling-derived cotelydon, cotyledonary node and hypocotyl explants.
Ani, Abosede O. +3 more
core +1 more source