Results 61 to 70 of about 3,716,507 (339)

The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum

open access: yesFEBS Letters, EarlyView.
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti   +3 more
wiley   +1 more source

Explicit tracking of uncertainty increases the power of quantitative rule-of-thumb reasoning in cell biology [PDF]

open access: yesBiophys. J. 107 2612 (2014), 2014
"Back-of-the-envelope" or "rule-of-thumb" calculations involving rough estimates of quantities play a central scientific role in developing intuition about the structure and behaviour of physical systems, for example in so-called `Fermi problems' in the physical sciences.
arxiv   +1 more source

Check list of ground-dwelling ant diversity (Hymenoptera: Formicidae) of the Iguazú National Park with a comparison at regional scale [PDF]

open access: yes, 2015
We describe the ant fauna of Iguazú National Park (INP), a region of high biodiversity andendemism in northeastern Argentina that includes the southernmost protected area ofthe Atlantic Forest (AF).
Achury, R.   +6 more
core   +2 more sources

Use of collective expertise as a tool to reinforce food safety management in Africa [PDF]

open access: yes, 2020
The Erasmus+ project (2017-2020) entitled Societal Challenges and Governance of African Universities: the case of ALIments in Morocco, the Democratic Republic of the Congo and Senegal (DAfrAli) seeks to strengthen the governance capacity of African ...
Barreto Crespo, Maria-Teresa   +12 more
core   +2 more sources

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

open access: yesFEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan   +10 more
wiley   +1 more source

A PEROXO-Tag Enables Rapid Isolation of Peroxisomes from Human Cells

open access: yesiScience, 2020
Summary: Peroxisomes are metabolic organelles that perform a diverse array of critical functions in human physiology. Traditional isolation methods for peroxisomes can take more than 1 h to complete and can be laborious to implement.
G. Jordan Ray   +6 more
doaj  

A new murine esophageal organoid culture method and organoid-based model of esophageal squamous cell neoplasia

open access: yesiScience, 2021
Summary: Organoids mimic the physiologic and pathologic events of organs. However, no consensus on esophageal organoid (EO) culture methods has been reached.
Biyun Zheng   +11 more
doaj  

The Nature of Biology in Life Sciences Undergraduate Courses

open access: yesRevista de Ensino de Ciências e Matemática, 2022
The research deals with the relationship between the initial training of biology teachers and the Nature of Biology, aiming to analyze the Pedagogical Projects of two Undergraduate Courses in Biological Sciences of a university in northeastern Brazil in
Ana Júlia Soares Santana   +3 more
doaj   +1 more source

Spot‐14 and its paralog Spot‐14R regulate expression of metabolic and thermogenic pathway genes in murine brown and beige adipocytes

open access: yesFEBS Letters, EarlyView.
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez   +3 more
wiley   +1 more source

PCR-based profiling of transcription factor activity in vivo by a virus-based reporter battery

open access: yesiScience, 2022
Summary: Understanding the molecular mechanisms of gene regulation is pivotal for understanding how cells establish and modify their identities and functions.
Hitomi Abe, Kentaro Abe
doaj  

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