Results 51 to 60 of about 1,338,720 (273)

Infection Control Practices for Vascular Access Management in Hemodialysis: Results From a Nationwide Survey of Japanese National University Hospitals

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Bloodstream infections due to repeated vascular access (VA) puncture and circuit connections remain major concerns in hemodialysis. Therefore, we examined current practices for glove, disinfectant, and personal protective equipment (PPE) use according to VA type in national university hospitals in Japan.
Aiko Yamada, Makoto Harada, Tadahiko Kikugawa, Takeshi Nakata, Koji Hashimoto, Tsuneo Konta, Yuji Kamijo   +6 more
wiley   +1 more source

High-content imaging of primary chronic lymphocytic leukemia cells predicts patient cohorts with distinct cellular drug responses

iScience
Summary: Cancer precision medicine benefits from identifying biomarkers that can predict therapy response. However, within a population of chronic lymphocytic leukemia (CLL) patients, there is heterogeneity that is inherent to the disease and also ...
Mark X. Li, Glauber C. Brito, Jarkko Ylanko, Alla Buzina, Brian Leber, Sila Usta, Hubert Tsui, David E. Spaner, David W. Andrews   +8 more
doaj   +1 more source

Developing lifelong learners: A novel online problem‐based ultrasonography subject [PDF]

, 2000
Online learning environments have a major role in providing lifelong learning opportunities. Lifelong learning is critical for successful participation in today's competitive work environment.
Koppi, Anthony, Minasian‐Batmanian, Laura, Pearson, Elaine   +2 more
core   +3 more sources

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Team-Based Learning and Threshold Concepts in Biological Security and Dual-Use: Toward a Transformative Biological Security Pedagogy—The Game Changing Implications of CRISPR/Cas and the Design of a Novel Methodology for Influencing the Culture of Life and Associated Science through Awareness Raising and Education

Creative Education
Yes CRISPR (clustered regularly interspaced short palindromic repeats) gene editing technologies appear to be a game-changer and suggest great potential for genome manipulation and for developments in next-generation therapeutics. Ethical, legal and social concerns have been raised in light of recent applications in humans.
Whitby, Simon, Dando, Malcolm, McCarter, Rebecca, Tweddell, Simon   +3 more
openaire   +3 more sources

HIV-1 env gene mutations outside the targeting probe affects IPDA efficiency

iScience
Summary: The intact proviral DNA assay (IPDA) based on droplet digital PCR was developed to identify intact proviral DNA and quantify HIV-1 latency reservoirs in patients infected with HIV-1.
Zehua Zhou, Xinyu Zhang, Meiyu Wang, Fei Jiang, Jincheng Tong, Jianhui Nie, Chenyan Zhao, Haifa Zheng, Zhen Zhang, Penghui Shi, Weiguang Fan, Youchun Wang, Weijin Huang   +12 more
doaj   +1 more source

Understanding Science Through Knowledge Organizers: An Introduction [PDF]

, 2004
We propose, in this paper, a teaching program based on a grammar of scientific language borrowed mostly from the area of knowledge representation in computer science and logic.
G., Nagarjuna, Kharatmal, Meena
core  

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

A rationally designed optochemogenetic switch for activating canonical Wnt signaling

iScience, 2023
Summary: Accurate spatiotemporal control of multicellular self-organization by various signaling pathways is essential for developmental stages. In particular, evolutionarily conserved Wnt signaling serves as a major morphogenetic switch to determine the
Seunghwan Lee, Mingguang Cui, Donghun Lee, Kihoon Han, Woong Sun, Dongmin Lee   +5 more
doaj   +1 more source

Mind-life continuity: a qualitative study of conscious experience [PDF]

, 2017
There are two fundamental models to understanding the phenomenon of natural life. One is thecomputational model, which is based on the symbolic thinking paradigm. The other is the biologicalorganism model.
Hipólito, Inês, Martins, J.
core   +1 more source