CORE: Cholesterol Altered Lipid Nanoparticles for Splenic Expression of mRNA Payloads
In this paper researchers introduce CORE LNPs, a new class of lipid nanoparticles engineered to redirect mRNA expression away from the liver and into the spleen, a key immune organ. By combining chemical design with computational tools, they created cholesterol analogs that enable precise spleen‐targeted expression, providing greater applications for ...
Eshan A. Narasipura +4 more
wiley +1 more source
Assessing content validity of learner milestones for decolonial global health education: A modified Delphi study. [PDF]
Edwards JG +12 more
europepmc +1 more source
Microengineered Gradient Hydrogels for Mechanobiology
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong +4 more
wiley +1 more source
Schematic illustration of the SH bandage placed on an infected burn wound and its role in wound healing. A superhydrophobic PDMS membrane coated with the PS verteporfin is placed over the wound area and illuminated with a red laser at 690 nm, generating airborne 1O2 above the tissue.
Fernanda Viana Cabral +8 more
wiley +1 more source
Patients Reported Adverse Effects of Antidepressants Among Depressive Disorder and Associated Risk Factors: A Multicenter Cross-Sectional Study. [PDF]
Chanie GS +10 more
europepmc +1 more source
Gonzalez Martinez and collaborators develop a strategy to formulate high performance GelMA‐based bioinks with low solids contents. The resulting bioinks enable 3D bioprinting at 37 °C of high‐fidelity structures with tunable mechanical properties that support high cell viability and function.
David A. González‐Martínez +8 more
wiley +1 more source
Mapping the evidence on post-intensive care syndrome in paediatric populations: A scoping review protocol. [PDF]
Hassan S, Hassan A.
europepmc +1 more source
Book Club at a medical school in the Sertão Region of Rio Grande do Norte State, Brazil. [PDF]
Sampaio AL +4 more
europepmc +1 more source
Integration of PrEP dispensing with HIV self-testing among heterosexual men in Sub-Saharan Africa: protocol for a scoping review. [PDF]
Hlongwa M, Tsai AC, Choko A.
europepmc +1 more source
Correction: GBR assisted <i>in situ</i> Onlay bone grafting for the posterior mandible horizontal ridge augmentation: a case report and literature review. [PDF]
Li M +8 more
europepmc +1 more source

