Results 91 to 100 of about 3,666,287 (295)

Good, bad, different or something else? A scoping review of the convictions, conventions and developments around quality in qualitative research

Royal Society Open Science
We present a scoping review of methodological papers in the social science literature covered in Scopus from 2017 to 2022. In this review, we document the shared norms, ideals and practices regarding the quality of qualitative research methodology.
Xavier Salet, John Gelissen, Guy Moors, Jelte Wicherts   +3 more
doaj   +1 more source

The determinants of footballers' effectiveness in a German club

Quality in Sport, 2019
The assessment of footballers effectiveness is the key element of control at every step of their training, regardless of on what level they are. What seems essential is the prediction of footballers' actions, the height of which is achieved in the time ...
Paweł Kalinowski, Sebastian Kalinowski, Damian Jerszyński, Monika Nowakowska, Jan Konarski, Dariusz Pietranis   +5 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Impact of question order on prioritisation of outcomes in the development of a core outcome set: a randomised controlled trial

Trials, 2018
Background Core outcome set (COS) developers increasingly employ Delphi surveys to elicit stakeholders’ opinions of which outcomes to measure and report in trials of a particular condition or intervention.
Sara T. Brookes, Katy A. Chalmers, Kerry N. L. Avery, Karen Coulman, Jane M. Blazeby, on behalf of the ROMIO study group   +5 more
doaj   +1 more source

Methodology of Science

Abstract Over our species’ history, we evolved methodological abilities of the mind (observation, problem solving and experimentation) that we use together with increasingly complex methods developed using these abilities (controlled experimentation, statistics and X-ray methods).
openaire   +1 more source

Applying Graph Theory to Examine the Dynamics of Student Discussions in Small-Group Learning. [PDF]

, 2019
Group work in science, technology, engineering, and mathematics courses is an effective means of improving student outcomes, and many different factors can influence the dynamics of student discussions and, ultimately, the success of collaboration.
Chai, Albert, Le, Joshua P, Lee, Andrew S, Lo, Stanley M   +3 more
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Development of an international survey attitude scale: measurement equivalence, reliability, and predictive validity

Measurement Instruments for the Social Sciences, 2019
Declining response rates worldwide have stimulated interest in understanding what may be influencing this decline and how it varies across countries and survey populations.
Edith de Leeuw, Joop Hox, Henning Silber, Bella Struminskaya, Corrie Vis   +4 more
doaj   +1 more source