Results 81 to 90 of about 3,666,287 (295)
Moving towards appropriability of academic knowledge: a post-actionalist perspective [PDF]
Based on recent contributions in managerial research, this article aims to suggest a new perspective for appraising and developing knowledge usability by studying the processes underlying its production: appropriation.
Grimand, Amaury +1 more
core +1 more source
Case studies: understanding players and the contexts in which they play. Workshop on Crossing Domains: Diverse Perspectives on Players [PDF]
, 2015 Over recent years, the study of games and players has become an established domain with HCI research. However, while a range of methods has been employed within this area, questions remain as to how to develop in-depth understandings of players and the ...
Cox, Anna, Iacovides, Ioanna
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The use of qualitative research in security sciences. Part I
Journal of Modern ScienceObjectives The aim of this article is to explain the essence of qualitative research in terms of its broader applicability, including in security sciences. Material and methods To explain the problem, they mainly used the method of examining the content
Andrzej Czupryński +1 more
doaj +1 more source
The creation and utilization of a physical science tablet application in the primary classroom [PDF]
, 2013 In traditional science education, lecture-style presentation dominates. There is a call, however, to integrate a greater amount of inquiry and discovery into the science classroom, specifically utilizing new media and technology.
Erhart, Sarah Elizabeth
core +2 more sources
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Lab Experiments Are a Major Source of Knowledge in the Social Sciences [PDF]
Laboratory experiments are a widely used methodology for advancing causal knowledge in the physical and life sciences. With the exception of psychology, the adoption of laboratory experiments has been much slower in the social sciences, although during ...
Falk, Armin, Heckman, James J.
core +6 more sources
Methodology of civil law science
The Journal of V. N. Karazin Kharkiv National University, Series "Law", 2019 The article deals with the methods of scientific researches in civil law such as dialectic, method of formal logic and method of structural system. The characteristics of these methods are also studied. The article supports thesis on dialectic being the most common method in legal researches, while other methods of scientific knowledge complete ...
openaire +3 more sources
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source