Results 161 to 170 of about 3,666,287 (295)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

A Study Protocol: Engagement of Lived Experience Voices for Analysis of Transformative Evidence in Mental Health Policy & Legislation (ELEVATE-MH). [PDF]

PLoS One
Sokoto KC, Masai TW, Gwanya-Mdletye SS, Silaule O, Jili SPP, Tessema SA, Rafique M, Lepkeh G, Amos A, Kariuki K, Solomon Y, Ghebrehiwet S, Valentine SE, Henderson DC, Harris B, Bonginkosi C, Pickersgill M, Manda-Taylor L.   +17 more
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

PubMed: an untapped source for open educational resource images. [PDF]

J Med Libr Assoc
Svoboda E, Connolly T.
europepmc   +1 more source

Methodology of Information Science

Proceedings of The 4th International Conference on the Foundations of Information Science, 2010
openaire   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Correction: Uridine diphosphate drives myeloid differentiation and functional reprogramming through dynamic transcriptional network. [PDF]

Front Immunol
Giordano C, Gentile D, Straface E, Gallo R, Cristiani CM, Abatino A, Pastore A, Celano M, Arcucci A, Albano F, Falco G, Veneziano C, Santamaria G, Aversa I, Isdraele Romano L, Palmieri C, Fiume G.   +16 more
europepmc   +1 more source

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha, Bishwas Mandal, Vishal Mandal, Asis Shrestha, Amir Babu Shrestha   +4 more
wiley   +1 more source

Treatment of a dentigerous cyst with autologous tooth grafting and platelet-rich plasma: a case report. [PDF]

J Surg Case Rep
Escoto-Vasquez LS, Romero-Lecanda JA, Lomelí-Martínez SM, Martínez-Nieto M, Heboyan A, Alarcón-Sánchez MA.   +5 more
europepmc   +1 more source