Results 151 to 160 of about 1,465,762 (307)
The Sufi journey towards nondual self-realization [PDF]
, 2010 viii, 253 leaves ; 29 cmSufism is a living mystical tradition with tools and a theoretical framework geared to facilitate the realization of one’s full potential.
University of Lethbridge. Faculty of Health Sciences +1 more
core
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
BHS573: Research Methodology / Faculty of Health Sciences [PDF]
The aim of the course is to interactively engage students cognitively and scientifically in areas of study design, measurement principle, measurement tools, reliability and validity of measurements, type of variables, sampling methods, and ethical issues
UiTM, Faculty of Health Sciences
core
Designed for life : disabled/enabled at home [PDF]
, 2008 x, 98 leaves ; 29 cm. --Using a phenomenological hermeneutic methodology, this thesis describes the lived experience of people with mobility impairments in the context of their home environment. Nine individuals with mobility impairments were interviewed
Perry, Jill +1 more
core
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
BHS570: Research Methodology / Faculty of Health Sciences [PDF]
The aim of the course is to interactively engage students cognitively and scientifically in areas of study design, measurement principle, measurement tools, reliability and validity of measurements, type of variables, sampling methods, and ethical issues
UiTM, Faculty of Health Sciences
core
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source