Results 61 to 70 of about 3,630,829 (295)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Neuromarketing Methodologies of Marketing Science [PDF]

open access: yesFourth International Conference On Advances in Economics, Management and Social Study - EMS 2015, 2015
Studies of neuromarketing passed a decade, finding the insights and decision making process has not changed overnight. In our research, we have found that traditional marketing research has been failed, whereas neuromarketing as a contemporary issue going made an evolutionary history. Different methodologies are now being used to get the hidden unaware
MD RABIUL, MOHAMMAD OSMAN, S M, S M
openaire   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A Bayesian Structural Equation Model to Predict Quality of Life in European Older Adults

open access: yesEuropean Journal of Investigation in Health, Psychology and Education
The ultimate goal of developed societies is to age with quality of life, but this concept is broad, and few studies have addressed which variables specifically affect its dimensions.
José M. Tomás   +2 more
doaj   +1 more source

THIRD EVALUATION OF TESTS PUBLISHED IN SPAIN [PDF]

open access: yesPapeles del Psicólogo, 2015
In order to provide technical information on the tests published in Spain, and continuing with the evaluation of some of the tests that are most frequently used in this country, this paper describes the results of the third evaluation of psychological ...
Ana Hernández,   +3 more
doaj  

Research Methodologies for Management Sciences & Interdisciplinary Research in Contemporary World [PDF]

open access: yes
The charismatic trend attributed in the domain of interdisciplinary research and management sciences has resulted in the notable increase of research activities in these fields.
Hasan, Syed Akif   +2 more
core   +1 more source

How Far Can We Go Through Social System? [PDF]

open access: yes, 2004
The paper elaborates an endeavor on applying the algorithmic information-theoretic computational complexity to meta-social-sciences. It is motivated by the effort on seeking the impact of the well-known incompleteness theorem to the scientific ...
Situngkir, Hokky
core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy