Results 131 to 140 of about 14,063,414 (314)
Methods of measuring pH in alkaline cyanide plating baths
Maurice R. Thompson
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ADAPTATION OF THE MICRO-KJELDAHL METHOD FOR THE DETERMINATION OF NITROGEN IN PLANT TISSUES [PDF]
Neil W. Stuart
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This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani+14 more
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B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez+17 more
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Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
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Aksiologi Filsafat Ilmu dalam Pengembangan Keilmuan
Humans develop a set of knowledge. This is predicated on the fact that he needs it. Because people inevitably have to determine for yourself how he behaved towards the prerequisites-a precondition of his life, and because the whole of reality is ...
Maria Sanprayogi, Moh. Toriqul Chaer
doaj
The Scope of Sociology. I. The Development of Sociological Method [PDF]
Albion W. Small
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Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen+12 more
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