Results 51 to 60 of about 1,090,569 (315)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
A Method for Accelerating the HITS Algorithm
Journal of Advanced Computational Intelligence and Intelligent Informatics, 2010 We present a new method to accelerate the HITS algorithm by exploiting hyperlink structure of the web graph. The proposed algorithm extends the idea of authority and hub scores from HITS by introducing two diagonal matrices which contain constants that act as weights to make authority pages more authoritative and hub pages more hubby. This method works
Andri Mirzal, Masashi Furukawa
openaire +2 more sources
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Resolving high frequency anomalies of gas cloud using full waveform inversion
Annals of Geophysics, 2016 High resolution models with structurally improved results significant to the physical properties of rocks in geologically complex areas require advance modeling methodologies.
Srichand Prajapati, Deva Ghosh
doaj +1 more source
Algorithms and methods in differential algebra
Theoretical Computer Science, 1996 The first three sections provide a rather superficial survey of Risch theory, i.e., solving \(y'=f\) by elementary functions, and symbolically solving linear \(n\)th order differential equations. The sections 4 and 5 give a survey of problems related to polynomial vector fields \(V=V_x\partial_x+V_y\partial_y+V_z\partial_z\), with \(V_x,V_y,V_z\in ...
openaire +1 more source
Methods of Automatic Algorithm Generation [PDF]
, 2004 Many methods have been proposed to automatically generate algorithms for solving constraint satisfaction problems. The aim of these methods has been to overcome the difficulties associated with matching algorithms to specific constraint satisfaction problems. This paper examines three methods of generating algorithms: a randomised search, a beam search
Stuart Bain +2 more
openaire +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Methods and effective algorithms for solving multidimensional integral equations
Российский технологический журнал, 2022 Objectives. Integral equations have long been used in mathematical physics to demonstrate existence and uniqueness theorems for solving boundary value problems for differential equations. However, despite integral equations have a number of advantages in
A. B. Samokhin
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Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source