Results 71 to 80 of about 1,090,569 (315)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
A comprehensive evaluation of alignment algorithms in the context of RNA-seq. [PDF]
, 2012 Transcriptome sequencing (RNA-Seq) overcomes limitations of previously used RNA quantification methods and provides one experimental framework for both high-throughput characterization and quantification of transcripts at the nucleotide level.
Friedel, Caroline C. +8 more
core +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Annals of Geophysics, 2011 <p>This study presents the latest developments of an approach called ‘flash sourcing’, which provides information on the effects of an earthquake within minutes of its occurrence.
Laurent Frobert +5 more
doaj +1 more source
Two algorithms for the sieve method
Journal of Algorithms, 1991 Abstract We present two algorithms that implement the sieve method. The first one sieves numbers. It finds the numbers of objects that have exactly each number of properties. The second sieves sets. It finds the sets of objects that have exactly each number of properties.
openaire +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Intercomparisons of Long-Term Atmospheric Temperature and Humidity Profile Retrievals
Remote Sensing, 2019 This study builds upon a framework to develop a climate data record of temperature and humidity profiles from high-resolution infrared radiation sounder (HIRS) clear-sky measurements.
Jessica L. Matthews, Lei Shi
doaj +1 more source
Algorithmic Methods of Variational Calculus
Elektronika ir Elektrotechnika, 2007 In problems of automatic control system optimization it is required to determine the structure of controller, parameters or the law of reference value variation which would guarantee the required quality of control. Methods of variational calculus are often used to solve problems of optimal control when control objects are simple and have mathematical ...
Dambrauskas, Algirdas +1 more
openaire +2 more sources
The s-monotone index selection rules for pivot algorithms of linear programming
, 2012 In this paper we introduce the concept of s-monotone index selection rule for linear programming problems. We show that several known anti-cycling pivot rules like the minimal index, Last-In–First-Out and the most-often-selected-variable pivot rules are ...
Nagy, Adrienn +3 more
core +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source