Results 81 to 90 of about 1,260,485 (295)
Intercomparisons of Long-Term Atmospheric Temperature and Humidity Profile Retrievals
This study builds upon a framework to develop a climate data record of temperature and humidity profiles from high-resolution infrared radiation sounder (HIRS) clear-sky measurements.
Jessica L. Matthews, Lei Shi
doaj +1 more source
Explicit memory schemes for evolutionary algorithms in dynamic environments [PDF]
Copyright @ 2007 Springer-VerlagProblem optimization in dynamic environments has atrracted a growing interest from the evolutionary computation community in reccent years due to its importance in real world optimization problems.
Yang, S +2 more
core +1 more source
MITF maintains genome stability in nonmelanocyte lineages
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Algorithm Development of Temperature and Humidity Profile Retrievals for Long-Term HIRS Observations
A project for deriving temperature and humidity profiles from High-resolution Infrared Radiation Sounder (HIRS) observations is underway to build a long-term dataset for climate applications.
Lei Shi +4 more
doaj +1 more source
Algorithms and methods in differential algebra
The first three sections provide a rather superficial survey of Risch theory, i.e., solving \(y'=f\) by elementary functions, and symbolically solving linear \(n\)th order differential equations. The sections 4 and 5 give a survey of problems related to polynomial vector fields \(V=V_x\partial_x+V_y\partial_y+V_z\partial_z\), with \(V_x,V_y,V_z\in ...
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Genetic Algorithms: Genesis of Stock Evaluation [PDF]
The uncertainty of predicting stock prices emanates pre-eminent concerns around the functionality of the stock market. The possibility of utilising Genetic Algorithms to forecast the momentum of stock price has been previously explored by many ...
Rama Prasad Kanungo
core
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
A Method to Accelerate the Convergence of the Secant Algorithm [PDF]
We present an acceleration technique for the Secant method. The Secant method is a root-searching algorithm for a general function f. We exploit the fact that the combination of two Secant steps leads to an improved, so-called first-order approximant of the root. The original Secant algorithm can be modified to a first-order accelerated algorithm which
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