Results 61 to 70 of about 87,565,261 (298)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

A variable neighborhood search with an effective local search for uncapacitated multilevel lot-sizing problems [PDF]

open access: yes, 2014
In this study, we improved the variable neighborhood search (VNS) algorithm for solving uncapacitated multilevel lot-sizing (MLLS) problems. The improvement is two-fold.
Xu, Yuchun   +4 more
core   +1 more source

Chapter 11. Problems and Problem Solving in the Light of Context-based Chemistry

open access: yes, 2021
To achieve higher-order thinking and meaningful deep learning, problem solving is fundamental for students to master. If one wants to make students engaged in their own learning and their problem-solving process, interesting and relevant tasks are a ...
Broman, Karolina,, Karolina Broman
core   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Radial basis function based meshless methods for fluid flow problems

open access: yes, 2006
This thesis is concerned with the development of meshless methods using radial basis functions for solving fluid flow problems. The advantage of meshless methods over traditional mesh-based methods is that they make use of a scattered set of collocation ...
Chinchapatnam, Phani P.
core   +1 more source

TRAVEL OF A CIRCLE IN A TRIANGLE, AND THE TRIANGLE IN THE HOLLOW OR SELF COMPUTER DIRECTOR

open access: yesОткрытое образование (Москва), 2016
The article describes an unusual possibility to use animation to study numerical methods for solving mathematical problems. Animation is defi ned not only and not so much as the creation of animation clips, but direct «revival» of the results of the ...
Valerij F. Ochkov, Elena P. Bogomolova
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Modern Methods for Solving Nonconvex Optimal Control Problems

open access: yesИзвестия Иркутского государственного университета: Серия "Математика", 2014
The paper presents a few remarks on the evolution of Irkutsk’s school of O. V. Vasiliev on optimal control methods based on Pontryagin principle. Besides, one reviews some features of Pontryagin principle, in particular, its sufficiency and constructive ...
A.S. Strekalovsky
doaj  

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

Two New Extended PR Conjugate Gradient Methods for Solving Nonlinear Minimization Problems [PDF]

open access: yesمجلة التربية والعلم, 2014
In this paper, we have discussed and investigated two nonlinear extended PR-CG method which use function and gradient values. The two new methods involve the standard CG-methods and have the sufficient descent and globally convergence properties under ...
Abbas AL-Bayati, Rana AL-Kawaz
doaj   +1 more source

Home - About - Disclaimer - Privacy