Results 51 to 60 of about 83,883,403 (289)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Application of statistical methods for solving problems of construction materials science

open access: yesНанотехнологии в строительстве, 2020
In the areas of construction materials science, the most promising solution is a set of issues related to the study of the influence of conditions for the formation of the material structure, including the possibilities of its self-organization, on its ...
Aleksey D. Zhukov
doaj   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Spreadsheet Implementations for Solving Boundary-Value Problems in Electromagnetics [PDF]

open access: yes, 2010
Electromagnetics is arguably one of the most challenging courses in any electrical engineering curriculum. A solid foundation in vector calculus and a good intuition based on physical grounds are the normal requirements for a student to successfully ...
Sastry P Kuruganty, Mark A Lau
core  

TRAVEL OF A CIRCLE IN A TRIANGLE, AND THE TRIANGLE IN THE HOLLOW OR SELF COMPUTER DIRECTOR

open access: yesОткрытое образование (Москва), 2016
The article describes an unusual possibility to use animation to study numerical methods for solving mathematical problems. Animation is defi ned not only and not so much as the creation of animation clips, but direct «revival» of the results of the ...
Valerij F. Ochkov, Elena P. Bogomolova
doaj   +1 more source

Structured development of problem solving methods [PDF]

open access: yesIEEE Transactions on Knowledge and Data Engineering, 2001
This paper, published in one of the top journals in Computer Science, describes the UPML framework for modelling knowledge-based applications, which can be seen as the culmination of over twenty years of research in this area. UPML has shaped the field, providing the intellectual and formal basis for the WSMO framework, which is the cornerstone of ...
Dieter Fensel, Enrico Motta
openaire   +4 more sources

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Exploring the role that language plays in solving mathematical word problems for the Solomon Islands secondary school students [PDF]

open access: yes, 2010
Mathematics is described as language. There is a strong link between mathematics and English language. This study is concerned with the role of language factors and proficiency of students in comprehension and solving of word problems in the Solomon ...
Ambrose, Malefoasi
core  

Modern Methods for Solving Nonconvex Optimal Control Problems

open access: yesИзвестия Иркутского государственного университета: Серия "Математика", 2014
The paper presents a few remarks on the evolution of Irkutsk’s school of O. V. Vasiliev on optimal control methods based on Pontryagin principle. Besides, one reviews some features of Pontryagin principle, in particular, its sufficiency and constructive ...
A.S. Strekalovsky
doaj  

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