Results 101 to 110 of about 455 (194)

Tumor‐Derived LAMB3 Drives Immunosuppressive LRRC15+ Fibroblast Formation During Pancreatic Ductal Adenocarcinoma Development

Advanced Science, EarlyView.
A single‐cell atlas of pancreatic ductal adenocarcinoma development reveals progressive ductal‐fibroblast‐immune crosstalk. Tumor‐derived LAMB3 drives the formation of immunosuppressive LRRC15+ fibroblasts through the ITGB1/FAK/MAPK/FOSL2 signaling. Glycolytic reprogramming upregulates LAMB3 and correlates with LRRC15+ fibroblast enrichment.
Xuqing Shi, Hangqi Liu, Jianru Sun, Xiaoding Liu, Xinping Jv, Longyun Chen, Yuhan Zhang, Hui Zhang, Xudong Xing, Ruiyu Li, Xinyi Ke, Jun Wang, Xianglin Yin, Bohan Liu, Qixian Liu, Yuan Wang, Junliang Lu, Shiyi Liu, Junyi Pang, Yumeng Cai, Menghua Dai, Fan Bai, Huanwen Wu, Zhiyong Liang   +23 more
wiley   +1 more source

Adaptive bit placement for dual biometric using signature and finger print for DWT-DCT picture steganography. [PDF]

Sci Rep
Bhattacharya A, Welekar AR, Sarkar P, Bose R, Roy S, Mitra A.   +5 more
europepmc   +1 more source

Discovering a uniform functional trade-off of the CBC-type 2,3-oxidosqualene cyclases and deciphering its chemical logic. [PDF]

Sci Adv, 2023
Zhang F, Wang Y, Yue J, Zhang R, Hu YE, Huang R, Ji AJ, Hess BA, Liu Z, Duan L, Wu R.   +10 more
europepmc   +1 more source

HNRNPU K181 Lactylation Drives Cervical Cancer Growth by Upregulating PHGDH and Reprogramming Serine Metabolism

Advanced Science, EarlyView.
Lactate in cervical cancer induces HNRNPU K181 lactylation, opposed by NAA50‐mediated acetylation and suppressed by Pazopanib. This lactylation enhances HNRNPU binding to PHGDH pre‐mRNA exon 1, maintaining exon 1‐containing transcripts and mRNA stability, thereby activating serine metabolism.
Chang Zhang, Qingfei Meng, Hui Jiao, Huixin Liu, Xiangchao Wang, Honglan Zhou, Yishu Wang   +6 more
wiley   +1 more source

An open dataset for oracle bone character recognition and decipherment. [PDF]

Sci Data
Wang P, Zhang K, Wang X, Han S, Liu Y, Wan J, Guan H, Kuang Z, Jin L, Bai X, Liu Y.   +10 more
europepmc   +1 more source

A study of text-theoretical approach to S-box construction with image encryption applications. [PDF]

Sci Rep, 2023
Mahboob A, Nadeem M, Rasheed MW.
europepmc   +1 more source

Enzymatic DNA Reaction Networks for Orchestrating Stimuli‐Dependent Temporal Molecular Pulse

Advanced Science, EarlyView.
We present an enzymatic DNA reaction network (EDRN) that encodes nucleic‐acid targets in time, converting inputs into a universal strand and then into programmable transient fluorescence pulses. With time‐color multiplexing, EDRN enables single‐tube high‐plex nucleic acid detection and shows strong agreement with clinical sequencing across 32 specimens.
Jiayu Yang, Yali Chang, Zibin Chu, Linghao Zhang, Tengfang Zhang, Dai Erhei, Xin Su, Zhe Yin   +7 more
wiley   +1 more source

Comparison and verification of detection accuracy for late deceleration with and without uterine contractions signals using convolutional neural networks. [PDF]

Front Physiol
Sato I, Hirono Y, Shima E, Yamamoto H, Yoshihara K, Kai C, Yoshida A, Uchida F, Kodama N, Kasai S.   +9 more
europepmc   +1 more source

Securing Data in Multimode Fibers by Exploiting Mode-Dependent Light Propagation Effects. [PDF]

Research (Wash D C), 2023
Rothe S, Besser KL, Krause D, Kuschmierz R, Koukourakis N, Jorswieck E, Czarske JW.   +6 more
europepmc   +1 more source