Results 31 to 40 of about 254,817 (266)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Stressful Events in Old Age: Who are Most Exposed and Who are Most Likely to Overcome Them
Gerontology and Geriatric Medicine, 2020 Objectives: This study investigated self-reported events that were rated as stressful and being affecting wellbeing among older people. It also examined the variables associated with the perception of overcoming these stressful events.
M. Soledad Herrera PhD +1 more
doaj +1 more source
Methods to Overcome the Limits of Management Theory
Економіка і регіон/ Economics and region, 2021 Scientific and technological advancements, as well as the rapid development of information technology, are bound to have an impact on business concepts. The changed socio-economic situation has led to the emergence of new and exacerbation of existing challenges and problems in management.
Aytan Asker Abasova +2 more
openaire +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Overcoming Recalcitrance: A Review of Regeneration Methods and Challenges in Roses
PlantsRoses (Rosa spp.) are among the most economically and ornamentally important floricultural crops worldwide, yet their improvement is constrained by inefficient breeding methods.
Anna Nelson +5 more
doaj +1 more source
METHODS FOR OVERCOMING SEED DORMANCY AND FEATURES OF IRIS CULTIVATION IN IN VITRO CONDITIONS
Известия высших учебных заведений. Поволжский регион: Естественные науки, 2020 Background. The state of organic seed dormancy is an important adaptation mechanism for the conservation of the species. However, the presence of deep dormancy makes the cultivation of many plants difficult. The development of methods and technologies
S. A. Soldatov, G. A. Karpova
doaj +1 more source
Ciência Florestal, 2014 http://dx.doi.org/10.5902/1980509814567This study aimed to evaluate the physiological and sanitary quality of seeds Lithraea molleoides (Vell.) Engl. comparing different methods to overcome dormancy.
Graziela Piveta +4 more
doaj +1 more source
Освітній дискурс, 2021 Urgency of the research is substantiated by the necessity for providing HEIs’ students with the opportunity to master foreign languages at least at level B2. Target setting.
Nataliia Shchur
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source