Results 51 to 60 of about 241,169 (264)

Automated zooplankton size measurement using deep learning: Overcoming the limitations of traditional methods

open access: yesFrontiers in Marine Science
Zooplankton size is a crucial indicator in marine ecosystems, reflecting demographic structure, species diversity and trophic status. Traditional methods for measuring zooplankton size, which involve direct sampling and microscopic analysis, are ...
Wenjie Zhang   +5 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Managements of different types of conflicts in creative collective [PDF]

open access: yesMarketing i Menedžment Innovacij, 2012
In article concept of conflicts arising in creative collective and work of advertisers with advertising agencies is considered, analysis of conflicts nature of, their classification and overcoming methods is carried out.
T.О. Bashuk, M.O. Khyzhnyak
doaj  

INNOVATION RESISTANCE AND METHODS OF OVERCOMING IT

open access: yes
This article presents the impact and importance of innovation on economic prosperity. The concept of resistance to innovation and the role of inertia in the innovation process are analyzed. The innovation process is discussed not only from the perspective of technical or technological changes but also from the perspective of institutional ...
Kutbedinov, Farhod, Niyatova, Iroda
openaire   +2 more sources

A Method for Overcoming ‘Unsoundness’ in Magnesian Limes [PDF]

open access: yesNature, 1952
BUILDING failures arising from the use of limes with a high content of magnesia have frequently been observed. These failures—such as spalling and blistering of plaster coats, disintegration of mortar joints and expansion of brickwork—are, according to Wells and others1,2, caused by the slow hydration of the magnesia in these ‘unsound’ limes, and may ...
openaire   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

CAUSES OF SOCIO-ECONOMIC CONFLICTS IN CUSTOMS AND METHODS OF OVERCOMING THEM

open access: yesВестник университета, 2016
The article discusses the concept of the school of human relations as tool for solving situations conflict in the customs authorities. Provides statistics on the results of analysis of the socio-economic conflicts.
A. Andrianov, V. Ovchinnikova
doaj  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

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