Results 51 to 60 of about 170,711,090 (240)

Visual information processing characteristics of tactical decisions of soccer players in 3V3 offense scenarios

BMC Sports Science, Medicine and Rehabilitation
Objective To quantitatively access the visual search of soccer players in the 3V3 offensive tactical situation and explore the eye movement characteristics and information processing mechanisms of high-level athletes under multi-target tracking.
Tianyu Gao, Peng Shi, Duoyao Zhang, Guodong Wang, Jianming Zhang   +4 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Classification of Seabed Types by OBIA With Recursive Feature Elimination Corrected by Expert Interpretation

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
The characteristics of seabed types are of great importance for understanding the marine environment and the changes taking place there, spatial planning, seabed investments, and natural resources extraction.
Karolina Trzcinska, Jan Matwiejczuk, Radoslaw Wroblewski, Aleksandra Malecha-Lysakowska, Maria Rucinska, Dominik Palgan, Marcelina Kasula, Jaroslaw Tegowski   +7 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Changing Bank Analysis Processes under the Influence of Artificial Intelligence Technologies

Учёт. Анализ. Аудит
The given article explores the areas of application of artificial intelligence (AI) focused on the transition from traditional periodic and expert methods of analysing bank activity to integrated autonomous data processing systems.The objective of the ...
T. N. Zverkova
doaj   +1 more source

Decision Support System Methods: A Review

Journal of Information Systems and Informatics, 2020
The current information system is the backbone of most companies or agencies. Currently there are various types of information systems including "transaction processing systems (TPS), office automation systems (OAS), knowledge work systems (KWS ...
Megawaty, Maria Ulfa
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Expert System for the Selection of the Rational Method for Collecting and Processing Information During Russian Census Based on Geographical and Socio-Economic Characteristics of Regions

Статистика и экономика, 2020
The article considers the issues of using new information and communication technologies (ICTs) when conducting the Russian Census related to the introduction of mobile devices and the Internet, which provide new opportunities for improving the quality ...
O. V. Manzhula
doaj   +1 more source