Results 111 to 120 of about 174,537,063 (257)

Frequency domain iterative feedforward/feedback tuning for MIMO ANVC

open access: yes, 2010
A new gradient estimation method is proposed that relies on efficient computation of the negative gradient of the average linear quadratic cost function completely in the frequency domain.
Veres, Sandor M.   +3 more
core   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

First-order methods of smooth convex optimization with inexact oracle [PDF]

open access: yes
In this paper, we analyze different first-order methods of smooth convex optimization employing inexact first-order information. We introduce the notion of an approximate first-order oracle.
GLINEUR, François   +2 more
core  

Optimum design of reinforced concrete rectangular columns subjected to axial compression and biaxial bending moments [PDF]

open access: yes, 2015
This study investigates the optimum design in terms of the minimum cost of reinforced concrete rectangular columns subjected to axial compression force and biaxial bending moments about x and y axes.
Mohammad, FA, Seyan, DA
core  

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

open access: yesFEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli   +3 more
wiley   +1 more source

Faster Double Adaptive Gradient Methods

open access: yes
In this paper, we propose a class of faster double adaptive gradient methods to solve nonconvex finite-sum optimization problems possibly with nonsmooth regularization by simultaneously using adaptive learning rate and adaptive mini-batch size ...
Luo, Yuning, Huang, Feihu
core   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Research on the Flow Field Characteristics of the Industrial Elliptical Cyclone Separator

open access: yesSeparations
A new type of elliptical cyclone separator has been proposed recently, but the flow field characteristics within the industrial device still need to be further investigated.
Yongli Zhang   +5 more
doaj   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

open access: yesFEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima   +7 more
wiley   +1 more source

Influence of Tire Characteristics of Interurban Taxis on Exposure Level to Drivers Whole-Body Vibrations

open access: yesMuhandisī-i bihdāsht-i ḥirfah/ī, 2016
Introduction: Taxi drivers’ exposure to repeat whole-body vibrations can cause back pain and digestive disorders. Since this type of vibration depends on the car components, this study was carried out to determine the influence of tire characteristics on
Milad Derakhshanjazari   +2 more
doaj  

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