Results 81 to 90 of about 20,004 (266)

PDIA6–SCD1 Axis Rewires Lipid Metabolism to Drive Gastric Cancer Progression

Advanced Science, EarlyView.
Protein disulfide isomerase A6 (PDIA6) is identified as an oncogenic driver in gastric cancer. PDIA6 directly binds and stabilizes SCD1 by limiting its ubiquitin–proteasome‐mediated degradation, thereby sustaining monounsaturated fatty acid (MUFA)‐enriched lipid homeostasis and lipid metabolic reprogramming.
Zhen Tian, Yifan Cheng, Jiajie Zhou, Ruiqi Li, Shuai Zhao, Ben Li, Zijie Xu, Mengli Zi, Yayan Fu, Chenkai Zhang, Qiannan Sun, Shantanu Baral, Sen Wang, Daorong Wang   +13 more
wiley   +1 more source

Synthesis and Stereostructure-Activity Relationship of Novel Pyrethroids Possessing two Asymmetric Centers on a Cyclopropane Ring

Molecules, 2019
2-Methylcyclopropane pyrethroid insecticides bearing chiral cyanohydrin esters or chiral ethers and two asymmetric centers on the cyclopropane ring, were synthesized.
Takashi Taniguchi, Yasuaki Taketomo, Mizuki Moriyama, Noritada Matsuo, Yoo Tanabe   +4 more
doaj   +1 more source

Molecular Mobility of N‐Acetylgalactosamine‐Modified Cyclodextrins on a Polyrotaxane for Highly Efficient Liver Targeting of Antibody Chimeras and Genome‐Editing Ribonucleoproteins

Advanced Science, EarlyView.
Monovalent N‐acetylgalactosamine (GalNAc)‐modified polyrotaxane enables efficient liver targeting by utilizing ligand mobility. The sliding and rotating cyclic components i.e., cyclodextrin in the polyrotaxane dynamically cluster GalNAc moieties, thereby mimicking trivalent interactions with asialoglycoprotein receptors.
Toru Taharabaru, Keiichi Motoyama, Yuting Wen, Zhongxing Zhang, Xuehao Tian, Jun Li, Taishi Higashi   +6 more
wiley   +1 more source

Effects of Thermal Sterilization Conditions on Flavor and Lipid Oxidation of Sauced Duck Necks

Foods
This study aimed to investigate the effect of thermal sterilization on the volatile flavor of sauced duck necks. The study revealed that thermal sterilization significantly reduced the content of unsaturated fatty acids (e.g., oleic acid C18:1n9c) in ...
Beibei Chu, Chao Zhang, Yushen Song, Hui Zhou, Xingguang Chen, Qianhui Gu   +5 more
doaj   +1 more source

Chemodiversity of L. from Kyrgyzstan: Isocoumarins, Coumarins, and Flavonoids from Aerial Parts

Natural Product Communications, 2008
A new accession of Artemisia dracunculus L., originating from Kyrgyzstan, has been analyzed for the first time regarding organ-specific accumulation of lipophilic compounds. Differences were found between leaves, stems, and inflorescences.
Tshering D. Bhutia, Karin M. Valant-Vetschera   +1 more
doaj   +1 more source

Alloevodionol methyl ether

Acta Crystallographica Section E Structure Reports Online, 2001
The crystal structure determination of one of the substituted α-chromene components isolated in the hexane extraction of the fruit of the indigenous Australian tree Melicope ellyrana, the methyl ether of the known compound alloevodionol, is reported.
Smith, Graham, Wang, Ertong, Bartley, John, Bott, Raymond   +3 more
openaire   +2 more sources

Sulfonated Bathocuproine Derivatives as Chemically Bonded Buried‐Interface Engineers for n–i–p Perovskite Solar Cells

Advanced Science, EarlyView.
A BCP‐derived buried‐interface strategy establishes Na‐BCS as a chemically bonded molecular bridge. By combining sulfonate anchoring to SnO2 with preserved BCP–Pb2+ coordination, Na‐BCS simultaneously passivates oxide‐ and perovskite‐side defects, suppresses non‐radiative recombination, and delivers a surface recombination velocity of 8.6 cm s−1, a ...
Dong Hyun Kim, Min Ju Jeong, SeungMin Lee, Oui Jin Oh, Mun Young Woo, Sung Yong Kim, Dong Hun Kang, Chan Young Kim, Chan Ho Shin, Jun Hong Noh   +9 more
wiley   +1 more source

Acetonitrile-hydrochloric acid hydrolysis of gangliosides for high performance liquid chromatographic analysis of their long chain bases.

Journal of Lipid Research, 1983
An improved method for the hydrolysis of long chain bases from gangliosides with aqueous acetonitrile-HCl is described. The long chain bases released from brain gangliosides were derivatized with biphenylcarbonylchloride and resolved by high performance ...
H Kadowaki, E G Bremer, J E Evans, F B Jungalwala, R H McCluer   +4 more
doaj   +1 more source

Donor Extended Blue TADF Dendrimer for High‐Performance Solution‐Processed OLEDs

Advanced Science, EarlyView.
A dendronized MR‐TADF emitter, DOBNA‐SpAc‐DCz, was designed to improve solubility, hole transport, and exciton dynamics for solution‐processed OLEDs. Incorporation of ter(tert‐butylcarbazole) dendrons decreases ΔEST and accelerates RISC, yielding short delayed lifetimes (∼2 µs).
Mahni Fatahi, Yuka Yasuda, Ryo Kondo, Hironori Kaji, Eli Zysman‐Colman   +4 more
wiley   +1 more source

Binary solvent participation in crystals of a multi-aromatic 1,2,3-triazole

Acta Crystallographica Section E: Crystallographic Communications
The X-ray crystal structure of a multi-aromatic substituted 1,2,3-triazole is presented, which shows an extensive three-dimensional hydrogen-bonding network involving two water molecules and two acetonitrile molecules. The structure of 4-{[(4-{[1-({[(3,4-
Jonathan Filley
doaj   +1 more source