Results 51 to 60 of about 30,207 (243)

Membrane Fusion‐Mediated Cytosolic Delivery of Threose Nucleic Acids via Homotypic Nanoparticles Overcomes Drug Resistance in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
This study introduces a biomimetic “nanofusion” platform that integrates the biostability of threose nucleic acids (TNA) with homotypic cell‐membrane cloaking to combat drug‐resistant TNBC. By leveraging a non‐canonical membrane‐fusion pathway for direct cytosolic delivery, the platform bypasses endosomal sequestration. To achieve potent AKT2 silencing
Wei Zheng   +7 more
wiley   +1 more source

Triazido[tris(2-pyridyl-κN)methylamine]cobalt(III)

open access: yesActa Crystallographica Section E, 2008
The title compound, [Co(N3)3(C16H14N4)], was synthesized by hydrothermal reaction of [Co(NH3)6](NO3)3, NaN3 and tris(2-pyridyl)methylamine. The structure contains two independent complexes in the asymmetric unit, with closely comparable geometry.
Xia Liu, Lujiang Hao
doaj   +1 more source

Lattice Coherency‐Driven (111)‐Oriented Wide Bandgap Perovskite Films

open access: yesAdvanced Energy Materials, EarlyView.
Methylammonium lead chloride (MAPbCl3)‐derived seed templates regulate wide‐bandgap perovskite crystallization through coupled thermodynamic and kinetic effects. Lattice‐coherent templating lowers the energy cost for (111) epilayer growth, while growth retardation controls crystallization kinetics, ultimately producing highly crystalline face‐up (111 ...
Yu‐Na Lee   +5 more
wiley   +1 more source

14C-Methylamine-glutaraldehyde conjugation as an alternative to iodination for protein labeling

open access: yesBioTechniques, 2003
Radiolabeling of native proteins conventionally has required iodination using 125Iodine (125I). Although radioiodination can result in high specific activity, there are several drawbacks in the use of 125I (e.g., radiological hazards and short half-life).
Penelope L. Moore   +2 more
doaj   +1 more source

Testing the ability of non-methylamine osmolytes present in kidney cells to counteract the deleterious effects of urea on structure, stability and function of proteins. [PDF]

open access: yesPLoS ONE, 2013
Human kidney cells are under constant urea stress due to its urine concentrating mechanism. It is believed that the deleterious effect of urea is counteracted by methylamine osmolytes (glycine betaine and glycerophosphocholine) present in kidney cells. A
Sheeza Khan   +5 more
doaj   +1 more source

Multiscale Perspectives on Perovskite Instability: From Atomistic Deformation to Device Degradation in Perovskite Solar Cells

open access: yesAdvanced Energy Materials, EarlyView.
Multiscale perspectives on how excess charges in soft lead halide perovskites induce operational instability in photovoltaic devices are presented. Localized carriers formed under thermodynamic non‐equilibrium states modify atomistic interactions and drive lattice distortions, accelerating device degradation.
Joo‐Hong Lee   +6 more
wiley   +1 more source

Sputtering Mechanism of an Unsintered Organic–Inorganic Sputtering Target for Perovskite Solar Cells

open access: yesAdvanced Energy Materials, EarlyView.
An unsintered MAPbI3 sputtering target fabricated via a mechanochemical route enables large‐area vacuum deposition of perovskite absorber layers, while revealing an ion–photon coupled decomposition mechanism that governs target erosion and film composition under RF plasma exposure.
Doha Lim   +9 more
wiley   +1 more source

THE ELECTRICAL CONDUCTIVITY OF METHYLAMINE SOLUTIONS. [PDF]

open access: yesJournal of the American Chemical Society, 1907
n ...
Franklin, E. C., Gibbs, H. D.
openaire   +2 more sources

Thermodynamics of Methylamine and Ammonia Synergy in Copper-Catalyzed Thiosulfate Gold Leaching

open access: yesMetals
Thiosulfate leaching is considered a promising alternative to cyanidation for gold extraction because it can be achieved at a low cost. However, existing leaching systems struggle to balance leaching efficiency with thiosulfate consumption.
Heng He   +8 more
doaj   +1 more source

Tandem Oligonucleotide Synthesis Enabled by a Reducible Linker. [PDF]

open access: yesChembiochem
Tandem oligonucleotide synthesis (TOS) of (chemically modified) DNA and RNA was achieved using a commercially available disulfide‐containing cleavable linker. The parent oligonucleotide sequences can be isolated with the disulfide linkage preserved. Subsequent reductive cleavage of the disulfide proceeds efficiently, yielding the corresponding strand ...
Sham AH   +3 more
europepmc   +2 more sources

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