Results 81 to 90 of about 4,912 (248)

Parallel Analysis of Acidic and Basic Proteoforms in Cell Lysates via Native Cation and Anion Exchange Chromatography—Native Mass Spectrometry

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Comprehensive characterization of proteoforms in complex biological systems remains a significant challenge. While native ion‐exchange chromatography (IEC) hyphenated with native mass spectrometry (nMS) is a powerful tool for resolving proteoforms, three critical limitations persist: restricted volatile buffers causing nonlinear pH gradients ...
Ziran Zhai   +5 more
wiley   +1 more source

(Retracted) Forms, Importance and Sources of Dissolved Organic Nitrogen (DON) in the Environment: A Review [PDF]

open access: yesSVU-International Journal of Engineering Sciences and Applications
Dissolved organic nitrogen (DON) is an integral part of the dissolved organic carbon (DOC) reservoir, encompassing substances with nitrogen content. Within aquatic ecosystems such as lakes and rivers, DON molecules originate from photosynthetic entities ...
Md Redowan Rashid   +3 more
doaj   +1 more source

Structural Insights Into the Function of Leishmania major Adenylosuccinate Lyase

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT One of several intriguing aspects of kinetoplastid biochemistry is the complete dependence on host purines and purine recycling due to the lack of a de novo purine biosynthesis pathway. Adenylosuccinate lyase (ASL, EC 4.3.2.2) is a key enzyme in the purine synthesis pathway responsible for the conversion of adenylosuccinate into adenosine ...
Ivan R. e Silva   +10 more
wiley   +1 more source

Bacterial flavin-containing monooxygenase is trimethylamine monooxygenase [PDF]

open access: yes, 2011
Flavin-containing monooxygenases (FMOs) are one of the most important monooxygenase systems in Eukaryotes and have many important physiological functions. FMOs have also been found in bacteria; however, their physiological function is not known.
Crombie, Andrew   +15 more
core   +1 more source

Merging Biocatalysis and Chemocatalysis in Flow: State‐of‐the‐Art and Future Directions for Sustainable Synthesis

open access: yesAngewandte Chemie, Volume 138, Issue 25, 15 June 2026.
This review highlights recent advances in integrating biocatalysis and chemocatalysis in continuous flow to create streamlined, sustainable processes. It examines chemo‐enzymatic cascades combining at least one enzymatic and one chemical step, discusses challenges such as enzyme immobilization, leaching, and reactor clogging, and presents solutions ...
Petros Siasiaridis   +2 more
wiley   +2 more sources

Impact of Stabilizing Osmolytes on the Conformational Dynamics of Human and Rat Islet Amyloid Polypeptides

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The aggregation of human islet amyloid polypeptide (hIAPP) into cytotoxic oligomers and amyloid fibrils is a hallmark of type 2 diabetes mellitus (T2DM), leading to pancreatic β‐cell dysfunction. In contrast, rat IAPP (rIAPP) is largely non‐amyloidogenic. Osmolytes such as glucose, glycerol, and sorbitol are known to stabilize globular protein
Kiara A. Kidman   +3 more
wiley   +1 more source

Copper-Catalyzed Formal C–N Bond Cleavage of Aromatic Methylamines: Assembly of Pyridine Derivatives

open access: yes, 2016
An efficient copper-catalyzed C–N bond cleavage of aromatic methylamines was developed to construct pyridine derivatives. With neat conditions and facile operation, the fragment-assembling strategy affords a broad range of 2,4,6-trisubstituted pyridines ...
Huawen Huang (1427662)   +4 more
core   +1 more source

The continuing significance of chiral agrochemicals

open access: yesPest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley   +1 more source

Carbonated Fluorapatite‐Gelatin‐Composites: Morphogenesis and Structure of Kniep's Dumbbells

open access: yesZeitschrift für anorganische und allgemeine Chemie, EarlyView.
Inspired by the pioneering work of Prof. Rüdiger Kniep on fluorapatite‐gelatin nanocomposites also known as “Kniep's Dumbbells,” this study investigates carbonated fluorapatite‐gelatin aggregates synthesized by the double diffusion technique within a gelatin gel.
Elena V. Sturm   +6 more
wiley   +1 more source

PREVENTION AND CONTROL OF DIMETHYLAMINE VAPORS EMISSION: HERBICIDE PRODUCTION PLANT [PDF]

open access: yesChemical Industry and Chemical Engineering Quarterly, 2008
The widely used herbicide, dimethylamine salt of 2,4-dichlorophenoxy acetic acid (2,4-D-DMA), is usually prepared by mixing a dimethylamine (DMA) aqueous solution with a solid 2,4-dichlorophenoxy acetic acid (2,4-D). The vapors of the both, reactants and
Zorana Arsenijević   +6 more
doaj  

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