Results 91 to 100 of about 7,237 (234)

Mechanistic Insight Into Ionizable Cationic Lipid‐Mediated Endosomal Escape via Transient Lipid Complexes

Small, EarlyView.
Coarse‐grained simulations show that the formation of transient anionic–cationic lipid pairs regulates the rate‐limiting step for the lamellar‐to‐hexagonal phase transition in mixtures of anionic and cationic lipids mimicking the endosomal membrane after fusion with lipid‐based nanoparticles, thus playing an important role in the endosomal escape of ...
David Noel Zimmer, Friederike Schmid, Giovanni Settanni   +2 more
wiley   +1 more source

Seasonal variation of aliphatic amines in marine sub-micrometer particles at the Cape Verde islands [PDF]

, 2009
Monomethylamine (MA), dimethylamine (DMA) and diethylamine (DEA) were detected at non-negligible concentrations in sub-micrometer particles at the Cap Verde Atmospheric Observatory (CVAO) located on the island of São Vicente in Cape Verde during algal ...
Gnauk, T., Herrmann, H., Iinuma, Y., Karstensen, Johannes, Lehmann, S., Müller, C., van Pinxteren, D.   +6 more
core   +1 more source

Comparison of Three Sympatric Desert Lizards: Digestive Tract Structure, Digestive Enzyme Activities, Gut Microbiota, and Metabolites

Integrative Zoology, EarlyView.
We performed 16S rDNA sequencing and metabolite profiling for three sympatric lizard species—Teratoscincus roborowskii, Phrynocephalus axillaris, and Eremias roborowskii—and compared their goblet cell and enzyme activities in the digestive tract. Our study suggests that the dietary niche may promote divergence or convergence of microbiota across host ...
Yi Yang, Ziyi Wang, Ruichen Wu
wiley   +1 more source

H2‐dependent modulation of tetrahydromethanopterin S‐methyltransferase (Mtr complex) activity by the small protein MtrR in Methanosarcina mazei

The FEBS Journal, EarlyView.
Small protein MtrR is a regulator of the Mtr methyltransferase complex in Methanosarcina mazei. It binds specifically to the MtrA subunit and modulates Mtr activity in response to hydrogen (H2) availability. Deleting mtrR impairs growth in the presence but not absence of H2, indicating its role in directing methyl transfer toward an energy‐conserving ...
Tim Habenicht, Bjarne Hastedt, Liam Cassidy, Claudia Kießling, Andreas Tholey, Jan M. Schuller, Ruth A. Schmitz   +6 more
wiley   +1 more source

Investigation into the delivery and evaluation of a unique Avena sativa (Oat) Lipid Extract on skin barrier using LC‒MS/MS, Raman spectroscopy, immunostaining analysis and skin efficacy

International Journal of Cosmetic Science, EarlyView.
Abstract Objectives Oat lipids are rich in ceramides. In this investigation, we analysed the delivery of a specific Oat Lipid Extract derived from Avena sativa, comprising ‘skin identical’ ratios of fatty acids, ceramides and cholesterol/sterol. This investigation is the first reported investigation of oat lipids utilizing Raman spectroscopy for the ...
E. Gombert, C. Dewis
wiley   +1 more source

Microbial−mammalian cometabolites dominate the age-associated urinary metabolic phenotype in Taiwanese and American populations [PDF]

, 2013
Understanding the metabolic processes associated with aging is key to developing effective management and treatment strategies for age-related diseases. We investigated the metabolic profiles associated with age in a Taiwanese and an American population.
Beckonert O., Bell J. D., Cannon J. G., Carmel R., Carol D. Ryff, Chadeau-Hyam M., Cho S., Christopher L. Coe, Clarke R., Coe C. L., Dana A. Glei, Davies K. M., Dean M., Elaine Holmes, Elsden S. R., Fukushima T., Goldman N., Hammar M. L., He F., Hebuterne X., Hehemann J. H., Holmes E., Hopkins M. J., Houtkooper R. H., Hurley B. F., Jeremy K. Nicholson, Jonathan R. Swann, Kaiser L. G., Kochhar S., Konstantina Spagou, Laidlaw S. A., Mariat D., Marmot M. G., Matthew Lewis, Maxine Weinstein, Mishur R. J., Muangpaisan W., Nicholson J. K., Noreen Goldman, Okuda Y., O’Sullivan O., Partridge L., Perrone R. D., Piper M. D., Psihogios N. G., Ramakrishna B. S., Ramakrishna B. S., Regitz-Zagrosek V., Robert L., Saude E. J., Slupsky C. M., Stanley E. G., Takiyama N., Teresa E. Seeman, Tiihonen K., Triantafyllou K., van den Bussche H., Veselkov K. A., Veselkov K. A., Vukovich M. D., Wald A., Walston J., Wang Y., Wang Z., Want E. J., Welshman S. G., Wijeyesekera A., Willets J. M., Williams A., Wolfe R. R., Yap I. K., Yasuda M., Zhang A. Q., Zhang F.   +73 more
core   +1 more source

Immune Evasion of Helicobacter pylori and Extra‐Gastric Cancer Risk

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Helicobacter pylori (H. pylori) is a group 1 gastric carcinogen that plays a significant role in extra‐gastric digestive system cancers. H. pylori disrupts host cell homeostasis through expression of virulence factors leading to immune evasion as well as persistent gastric mucosal colonization. H. pylori infection has been shown to play a role
Evren Doruk Engin, Ayse Basak Engin, Atilla Engin   +2 more
wiley   +1 more source

Microbial successions and metabolite changes during fermentation of salted shrimp (saeu-jeot) with different salt concentrations.

PLoS ONE, 2014
To investigate the effects of salt concentration on saeu-jeot (salted shrimp) fermentation, four sets of saeu-jeot samples with 20%, 24%, 28%, and 32% salt concentrations were prepared, and the pH, bacterial and archaeal abundances, bacterial communities,
Se Hee Lee, Ji Young Jung, Che Ok Jeon
doaj   +1 more source

Too close for comfort: Self‐crowding transforms protein structure and stability beyond volume exclusion

Protein Science, Volume 35, Issue 6, June 2026.
Abstract Proteins operate in crowded physiological environments, yet their conformational and oligomeric states are largely inferred from experiments performed under dilute buffer conditions. Here, we show that for lysozyme (LYS) and bovine serum albumin (BSA), self‐crowding at physiologically relevant concentrations alters protein structure and ...
Gil I. Olgenblum, Yehonatan N. Levy, Daniel Harries   +2 more
wiley   +1 more source

Genetic resources for methane production from biomass described with gene ontology

Frontiers in Microbiology, 2014
Methane (CH4) is a valuable fuel, constituting 70-95% of natural gas, and a potent greenhouse gas. Release of CH4 into the atmosphere contributes to climate change.
Endang ePurwantini, Trudy eTorto-Alalibo, Jane eLomax, João C. Setubal, João C. Setubal, Brett M. Tyler, Brett M. Tyler, Biswarup eMukhopadhyay, Biswarup eMukhopadhyay   +8 more
doaj   +1 more source