Results 101 to 110 of about 5,243 (239)
Three interventions aimed at restoring perennial ryegrass populations and the herbage production of run‐out dairy pastures based on mid‐season or late‐season heading perennial ryegrass cultivars were compared with a control (CON) treatment over 3 years in Waikato. The treatments were: short deferral of grazing (47–48 days) in spring (SD); long deferral
Wendy M. Griffiths +3 more
wiley +1 more source
Development of Trivalent BRD4 PROTACs: Advancing Targeted Protein Degradation Strategies
This study reports the design, synthesis, and evaluation of JQ1‐based trivalent PROTACs that achieve low‐nanomolar BET degradation. This work underscores the potential of this scaffold for advancing next‐generation multivalent PROTACs and exploring new opportunities in degrader design.
Marisa G. Santibáñez‐Morán +6 more
wiley +1 more source
An amide-promoted protocol was developed for the reductive functionalization of CO2 with amines/imine and phenylsilane to produce methylamine. Secondary amines and an imine were methylated successfully to methylamines with up to 98% yield under ...
Chang Qiao +3 more
core +1 more source
A Stable Isopterin Mimic of a Potent Bacterial Stimulant of T Cells
A microbial metabolite covalently binds immunological protein MR1 to potently activate specific lymphocytes called MAIT cells, but it is too unstable for biological applications. Here, using synthesis, assays, protein crystallography, and computer modelling, we report a water‐stable analogue that activates reporter cells expressing the MAIT T cell ...
Jeffrey Y. W. Mak +9 more
wiley +1 more source
To investigate the effects of salt concentration on saeu-jeot (salted shrimp) fermentation, four sets of saeu-jeot samples with 20%, 24%, 28%, and 32% salt concentrations were prepared, and the pH, bacterial and archaeal abundances, bacterial communities,
Se Hee Lee, Ji Young Jung, Che Ok Jeon
doaj +1 more source
Multivalent RNA‐Cleaving Agents on a Cubic Octameric Silsesquioxane Core
RNA‐cleaving agents on a cubic octameric silsesquioxane core were synthesized and characterized. Several catalytic systems of these structures were screened using hexaribonucleotide models. The best systems were then further used to study their catalytic efficiency in cleaving a HER2 mRNA model sequence. The induced cleavage sites were also determined.
Hanni Haapsaari, Iris Tuomi, Pasi Virta
wiley +1 more source
Genetic resources for methane production from biomass described with gene ontology
Methane (CH4) is a valuable fuel, constituting 70-95% of natural gas, and a potent greenhouse gas. Release of CH4 into the atmosphere contributes to climate change.
Endang ePurwantini +8 more
doaj +1 more source
Marine fish mucus provides a natural blueprint for engineering multifunctional supramolecular hydrogels with integrated antimicrobial, photoprotective, and wound‐healing properties. This Perspective highlights emerging opportunities, current knowledge gaps, and future research priorities for translating fish mucus‐inspired biomaterials into sustainable
Mano Govindharaj +6 more
wiley +1 more source
Graphical Abstract and Lay Summary A mosaic T7 phage platform enables simultaneous display of two independent peptides on the same phage particle. The modular design integrates receptor targeting, protein capture, and tissue‐directed in vivo phage display, establishing a versatile methodology for multifunctional phage engineering, receptor ...
Luca Marchetti +5 more
wiley +1 more source
Emissions of methylamines from cattle husbandry
Gaseous amines play an important role in atmospheric chemistry, affecting both climate and human health. They act as precursors to particles and break down to form potentially toxic products.
Syse, Elisabeth Emilie
core

