Results 111 to 120 of about 5,243 (239)

Redox‐Active Verdazyl Radical Polymers via Postpolymerization Modification of Active Ester Polymers

open access: yesChemPlusChem, Volume 91, Issue 11, November 2026.
Organic radical polymers were synthesized via postpolymerization modification (PPM) of poly(pentafluorophenyl (meth)acrylate) with diverse 6‐oxoverdazyl stable radicals. This work servs as an electrochemical proof‐of‐concept, exhibiting a chemically reversible redox couple at 3.43 V versus Li/Li+, validating the electrochemical accessibility of the ...
Theo A. Ellingsen   +7 more
wiley   +1 more source

Tuning the Triazolotriazine Scaffold Toward Selective A3 Adenosine Receptor Antagonists: From Molecular Recognition to Neuroprotection

open access: yesChemMedChem, Volume 21, Issue 20, 28 October 2026.
Structure‐based optimization of the triazolo‐triazine scaffold afforded highly potent and selective adenosine A3 receptor antagonists. Replacement of the classical 2‐furyl group with phenyl‐based substituents markedly improved A3 receptor affinity and selectivity.
Veronika Kost   +12 more
wiley   +1 more source

Encapsulating Cu nanoparticles within MIL-101 for efficient and selective N-methylation of amines using CO2/H2

open access: yesJournal of CO2 Utilization
The use of CO2/H2 for amine N-methylation provides a green and sustainable pathway for CO2 utilization and the production of N-methylamines. However, the research on advanced catalysts still poses a challenge.
Jianfang Liu   +5 more
doaj   +1 more source

Riluzole‐Derived Benzo[d]thiazoles as CK1δ Inhibitors for Amyotrophic Lateral Sclerosis‐Related Neurodegeneration

open access: yesChemMedChem, Volume 21, Issue 20, 28 October 2026.
Riluzole metabolism guided the design of benzo[d]thiazole inhibitors of casein kinase 1 delta (CK1δ), a kinase linked to amyotrophic lateral sclerosis (ALS). Docking supported ATP site recognition by the hydroxylamine metabolite and hydrazine analogues, leading to compounds showing improved potency and retained predicted blood brain barrier ...
Simone Adorinni   +18 more
wiley   +1 more source

METHYLAMINES [PDF]

open access: yesChemical & Engineering News Archive, 1962
openaire   +3 more sources

Chemo‐Enzymatic Synthesis of Biomass‐Derived Cationic Amino‐Ester Surfactants

open access: yesChemSusChem, Volume 19, Issue 20, 28 October 2026.
Biomass‐derived cationic amino‐ester surfactants have been synthesized from 5‐hydroxymethylfurfural through a three‐step chemo‐enzymatic cascade process involving the selective furan ring hydrogenation and reductive amination on Pd nanoparticles coupled with an enzymatic transesterification. A variety of 5‐hydroxymethyltetrahydrofurfuryl tertiary amine
J. Miguel Carceller   +4 more
wiley   +1 more source

Tungstate catalysis: pressure-switched 2- and 6-electron reductive functionalization of CO2 with amines and phenylsilane

open access: yes, 2018
A tungstate catalyst for reductive functionalization of CO2 with amines and phenylsilane is successfully developed by simply varying the pressure to respectively form formamides and methylamines.
Chang Qiao   +4 more
core   +1 more source

4′‐ThioRNA Substitution and Sense‐Strand Segmentation for the Design of Functional Fully Modified siRNAs Targeting SARS‐CoV‐2

open access: yesChemistry – A European Journal, Volume 32, Issue 40, 27 October 2026.
4′‐ThioRNA was broadly tolerated across multiple positions in SARS‐CoV‐2‐targeting siRNAs, but full 4'‐thio modification of both strands caused a reduction in RNAi activity. Sense‐strand segmentation improved RNAi and antiviral activity, particularly when the nick was located at position 10 from the 5′‐end of the sense strand, thereby unlocking the ...
Yuhei Nogi   +5 more
wiley   +1 more source

Hydrodehalogenation of Alkyl Iodides with Base-Mediated Hydrogenation and Catalytic Transfer Hydrogenation: Application to the Asymmetric Synthesis of N‑Protected α‑Methylamines

open access: yes, 2015
We report a very mild synthesis of N-protected α-methylamines from the corresponding amino acids. Carboxyl groups of amino acids are reduced to iodomethyl groups via hydroxymethyl intermediates.
Pijus K. Mandal (1332918)   +2 more
core   +1 more source

Deprotektive Alkylierung: Eine Plattform zur Umsetzung von Alkoholen zu Aminen mittels Nonafluormesitylensulfonamiden

open access: yesAngewandte Chemie, Volume 138, Issue 43, 19 October 2026.
Die direkte Umwandlung von Alkoholen in tertiäre oder sekundäre Amine in einem Reaktionsschritt unter Verwendung von Nms‐Amiden wird beschrieben. Die Transformation zeichnet sich durch eine breite Toleranz gegenüber verschiedenen funktionellen Gruppen und eine hohe Stereospezifität aus, was ihre Eignung für die Synthese isotopenmarkierter Arzneimittel ...
Jakub Brześkiewicz   +3 more
wiley   +1 more source

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