Results 121 to 130 of about 881,260 (340)

A Dnmt2-like protein mediates DNA methylation inDrosophila [PDF]

, 2003
Natascha Kunert, Joachim Marhold, Jonas Stanke, Dirk Stach, Frank Lyko   +4 more
openalex   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Decoding epigenetic markers: implications of traits and genes through DNA methylation in resilience and susceptibility to mastitis in dairy cows

Epigenetics
Cattle farming faces challenges linked to intensive exploitation and climate change, requiring the reinforcement of animal resilience in response to these dynamic environments.
Lotfi Bouzeraa, Helene Martin, Clement Plessis, Pascal Dufour, Jessica C. S. Marques, Sydney Moore, Ronaldo Cerri, Marc-Andre Sirard   +7 more
doaj   +1 more source

Magic methylation with methyl-containing peroxides

Chemical Science
Methyl groups are abundant in pharmaceuticals, and their installation has garnered significant attention. This review summarises advancements in the use of methyl-containing peroxides as reagents for a variety of methylation reactions.
Daliah Farajat, Yuhua Zhang, Chao-Jun Li
openaire   +2 more sources

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Effective Sliding Motions of Vibration‐Induced Emission Stoppers in Mechanically Interlocked Molecules as Artificial Muscle Tougheners and In Situ Molecular Shuttling Sensors for Self‐Healable Mechano‐Fluorescent Polyurethane Organogels

Advanced Functional Materials, EarlyView.
The self‐healable ratiometric mechano‐fluorescent polyurethane (PU) organogel is constructed by incorporating a minor amount (ca. 1.5 wt.%) of the unconventional daisy chain rotaxane (as an artificial molecular muscle toughener) with specific sliding motions and ratiometric emission behaviors into the PU skeleton, which reveals the progressed intrinsic
Tu Thi Kim Cuc, Yu‐Chen Lai, Trang Manh Khang, Wei‐Tsung Chuang, Tung‐Kung Wu, Ricardas Rotomskis, Simona Steponkiene, Hong‐Cheu Lin   +7 more
wiley   +1 more source

Diagnostic accuracy, clinical utility and influence on decision‐making of a methylation urine biomarker test in the surveillance of non‐muscle‐invasive bladder cancer [PDF]

, 2019
David D‘Andrea, Francesco Soria, Sonja Zehetmayer, Kilian M. Gust, Stephan Korn, J. Alfred Witjes, Shahrokh F. Shariat   +6 more
openalex   +1 more source

Conformal Polymer Electrolyte Enabled by Nitrile Coordination for Long‐Cycle Solid‐State Lithium Metal Batteries

Advanced Functional Materials, EarlyView.
The replacement of α‐H with methyl groups markedly improves the compatibility between the electrolyte and lithium metal, facilitating the formation of a conformal SEI layer that effectively accommodates volume variations in lithium metal during cycling.
Liyuan Huang, Liang Lan, Yifan Wu, Xin Ao, Naigen Zhou, Yi Zhou, Chengjin Peng, Yecheng Liu, Shan Fang, Stefano Passerini   +9 more
wiley   +1 more source

Chromatin dysregulation and DNA methylation at transcription start sites associated with transcriptional repression in cancers. [PDF]

, 2019
Although promoter-associated CpG islands have been established as targets of DNA methylation changes in cancer, previous studies suggest that epigenetic dysregulation outside the promoter region may be more closely associated with transcriptional changes.
Ando, Mizuo, Bui, Nam Q, Califano, Joseph A, Favorov, Alexander V, Fertig, Elana J, Fisch, Kathleen, Fukusumi, Takahito, Gaykalova, Daria A, Guo, Theresa, Ha, Patrick, Haft, Sunny, Ideker, Trey, Liu, Chao, Mark, Adam, Medetgul-Ernar, Kate, Messer, Karen, Pang, John, Pu, Minya, Ren, Shuling, Saito, Yuki, Sakai, Akihiro, Tamayo, Pablo, Xu, Guorong, Yamasoba, Tatsuya, Yegnasubramanian, Srinivasan   +24 more
core  

Offspring DNA methylation of the aryl-hydrocarbon receptor repressor gene is associated with maternal BMI, gestational age, and birth weight [PDF]

, 2015
Heather H. Burris, Andrea Baccarelli, Hyang‐Min Byun, Alejandra Cantoral, Allan C. Just, Ivan Pantic, Maritsa Solano-González, Katherine Svensson, Marcela Tamayo‐Ortiz, Yan Zhao, Robert O. Wright, Martha María Téllez‐Rojo   +11 more
openalex   +1 more source