Results 151 to 160 of about 881,260 (340)
DNA methylation analysis of WIF1 and DKK4 in cervical precancerous lesions and cancer
Journal of Education, Health and Sport, 2019 Epigenetic gene silencing by excessive methylation was found in many tumors. Methylation of tumor suppressor genes is often found in cervical cancer, which is an important pathogenetic factor of oncologic process.
I. Gladchuk +4 more
doaj
Geminivirus Rep Protein Interferes with the Plant DNA Methylation Machinery and Modifies the Host Epigenome [PDF]
, 2016 The apparent simplicity of viruses hides the complexity of their interactions with their hosts. Viruses are masters at circumventing host defenses and manipulating the cellular environment for their own benefit.
Castillo-Garriga, Araceli
core
Advanced Science, EarlyView.In macrophage‐myofibroblast transition, upregulated NNMT depletes S‐Adenosylmethionine (SAM) and nicotinamide adenine dinucleotide(NAD+), thereby triggering epigenetic reprogramming via Histone H3 Lysine 27 acetylation (H3K27ac) accumulation at the promoter region of master transcription factor Prrx1.
Xiwen Dong +11 more
wiley +1 more source
Inhibitor of CBP Histone Acetyltransferase Downregulates p53 Activation and Facilitates Methylation at Lysine 27 on Histone H3 [PDF]
, 2018 Adam Vincek +10 more
openalex +1 more source
Advanced Science, EarlyView.This study successfully establishes adamantinomatous craniopharyngioma (ACP) patient‐derived organoids (PDOs) that preserve the histopathological and genetic features of the original tumors. Through drug sensitivity assays and subsequent mechanistic analyses, the study demonstrates that Ceritinib exerts its inhibitory effects on ACP PDO growth by ...
Huarong Zhang +15 more
wiley +1 more source
How epigenetic evolution can guide genetic evolution (abstract)
, 2008 The expression level of a gene in future generations can be modified both by genetic mutations and by the attachment of methyl groups to the DNA. Since the DNA methylation pattern along a genome is inherited, methylation patterns constitute a significant
Groom, Graeme +2 more
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