Results 161 to 170 of about 1,069,555 (390)

Practical implementation of DNA methylation and copy-number-based CNS tumor diagnostics: the Heidelberg experience

Acta Neuropathologica, 2018
Recently, we described a machine learning approach for classification of central nervous system tumors based on the analysis of genome-wide DNA methylation patterns [6].
D. Capper, D. Stichel, F. Sahm, David T. W. Jones, D. Schrimpf, M. Sill, S. Schmid, V. Hovestadt, D. Reuss, C. Koelsche, A. Reinhardt, A. Wefers, Kristin Huang, P. Sievers, A. Ebrahimi, A. Schöler, D. Teichmann, A. Koch, D. Hänggi, A. Unterberg, M. Platten, W. Wick, O. Witt, T. Milde, A. Korshunov, S. Pfister, A. von Deimling   +26 more
semanticscholar   +1 more source

Fibrillar Bundles as Fibrous Filler Materials for Attaining Cell Anisotropy in Bioprinting

Advanced Healthcare Materials, EarlyView.
Fibrillar bundles are introduced as a bioprintable additive that enables robust and scalable cellular alignment within 3D constructs through flow‐induced orientation during extrusion. These fibers support strong cell adhesion and polarization across various cell types and significantly enhance myotube alignment in Gelatine‐Methacryloyl (GelMA ...
Sven Heilig, Zan Lamberger, Lys Sprenger, Vivien Priebe, Camilla Mussoni, Denitsa Docheva, Kristina Andelovic, Jürgen Groll, Sahar Salehi, Gregor Lang, Matthias Ryma   +10 more
wiley   +1 more source

Fusarium BP1 is a reader of H3K27 methylation [PDF]

, 2021
Guangfei Tang, Jianlong Yuan, Jing Wang, Yizhe Zhang, Sisi Xie, Hongkai Wang, Tao Zeng, Huiquan Liu, Harold Kistler, Youfu Zhao, Cheng‐Guo Duan, Wende Liu, Zhonghua Ma, Yun Chen   +13 more
openalex   +1 more source

Characterization of Microplastics in Human Gastric Cancer and Control Tissues and Analysis of Associated Genetic Features

Advanced Healthcare Materials, EarlyView.
This study characterizes the presence of microplastics in human normal gastric, para‐tumor, and gastric tumor tissue and confirms the association between microplastic exposure and lymph node metastasis in gastric cancer. This study explores the transcriptomic changes induced by microplastic exposure, laying the foundation for further investigation into
Liqiao Chen, Jialin Li, Yan Wu, Han Bao, Xuesong Yang, Guoqing Lv, Ke Ji, Ji Zhang, Xiaojiang Wu, Kai Zhou, Jieli Xu, Jiatian Tang, Xiyuan Han, Anqiang Wang   +13 more
wiley   +1 more source

Chromatin dysregulation and DNA methylation at transcription start sites associated with transcriptional repression in cancers. [PDF]

, 2019
Although promoter-associated CpG islands have been established as targets of DNA methylation changes in cancer, previous studies suggest that epigenetic dysregulation outside the promoter region may be more closely associated with transcriptional changes.
Ando, Mizuo, Bui, Nam Q, Califano, Joseph A, Favorov, Alexander V, Fertig, Elana J, Fisch, Kathleen, Fukusumi, Takahito, Gaykalova, Daria A, Guo, Theresa, Ha, Patrick, Haft, Sunny, Ideker, Trey, Liu, Chao, Mark, Adam, Medetgul-Ernar, Kate, Messer, Karen, Pang, John, Pu, Minya, Ren, Shuling, Saito, Yuki, Sakai, Akihiro, Tamayo, Pablo, Xu, Guorong, Yamasoba, Tatsuya, Yegnasubramanian, Srinivasan   +24 more
core  

The First Review on Nano‐Agricultural Applications of MXene and MBene‐Based Materials for Plant‐Immunoengineering, Controlled Protection, and Inducing Biostimulation Mechanisms

Advanced Materials, EarlyView.
MXene and MBene nanomaterials show significant potential in addressing critical challenges in biomedicine, applied biology, agriculture, and the environment. From a nano‐agricultural perspective, this relatively young field has witnessed emerging advances towards applications for plant‐immunoengineering, biostimulation, and controlled delivery ...
Alireza Rafieerad, Ahmad Amiri, Maik Böhmer, Soofia Khanahmadi   +3 more
wiley   +1 more source

Detection of rare mutations, copy number alterations, and methylation in the same template DNA molecules

, 2023
Yuxuan Wang, Christopher Douville, Joshua D. Cohen, Austin K. Mattox, Sam Curtis, Natalie Silliman, Maria Popoli, Janine Ptak, Lisa Dobbyn, Nadine Nehme, Jonathan C. Dudley, Mahmoud Summers, Ming Zhang, Lan T. Ho‐Pham, Ngoc Bich Tran, Thach Tran, Tuan V. Nguyen, Chetan Bettegowda, Nickolas Papadopoulos, Kenneth W. Kinzler, Bert Vogelstein   +20 more
openalex   +1 more source

Enrichment of Hypermethylated DNA on Chip for Cervical Cancer Detection

Advanced Materials Interfaces, EarlyView.
A microfluidic chip coated with surface‐immobilized methyl binding domain 2 (MBD‐2) protein receptors, is able to bind hypermethylated DNA (hmDNA) from a cancer cell line selectively. Quantification by quantitative polymerase chain reaction (qPCR) shows a 30‐fold enrichment in cervical cancer target DNA.
Ruben W. Kolkman, Birgit M. M. Wever, Jeanne Elisabeth van Dongen, Annina P. van Splunter, Johan G. Bomer, Renske D. M. Steenbergen, Loes I. Segerink, Jurriaan Huskens   +7 more
wiley   +1 more source

DNA methylation: a historical perspective.

Trends in Genetics, 2022
Alexandra L. Mattei, Nina Bailly, A. Meissner   +2 more
semanticscholar   +1 more source

Exploring the Impact of the Presence of 9,9′‐Spirobifluorene Moieties on the Performance of Carbonyl‐Based Multiresonant Thermally Activated Delayed Fluorescence Organic Light‐Emitting Diodes

Advanced Optical Materials, EarlyView.
The impact of decorating the multiresonant thermally activated delayed fluorescence (MR‐TADF) emitter DiKTa with 9,9′‐spirobifluorene units is explored with regard to number, position, and incorporation type. Four novel sky‐blue narrowband MR‐TADF emitters are developed, and in the OLED devices, a structure‐property relationship is observed with ...
Janine Haug, Sen Wu, Hassan Hafeez, Maximilian Schustek, Mahni Fatahi, Yannik T. Woordes, Martin Nieger, Olaf Fuhr, Burkhard Luy, Ifor D.W. Samuel, Stefan Bräse, Eli Zysman‐Colman   +11 more
wiley   +1 more source