Results 171 to 180 of about 652,669 (356)

The Pectic Acid from the Pulp of Jackfruit (Artocarpus Integrifolia). I. Methylation Studies [PDF]

, 1963
Usha Gupta, C.V. Narasimha Rao
openalex   +1 more source

Biological methylation

Quarterly Reviews, Chemical Society, 1945
openaire   +3 more sources

LEDGF Binds H3R17me2a Promoting De Novo Nucleotide Biosynthesis in SETD2 Mutant Clear Cell Renal Cell Carcinoma

Advanced Science, EarlyView.
In SETD2‐mutant ccRCC, the original LEDGF recognition of the H3K36me3 regulatory axis no longer exists. LEDGF interacts with CARM1‐dependent H3R17me2a regulating the transcription of key enzymes in the de novo synthesis pathway. The abnormally elevated LEDGF leads to the accumulation of purine nucleotides in SETD2‐mutant ccRCC, thereby satisfying the ...
Yuwei Zhang, Yuhua Zhou, Yuezhou Zhang, Jing Lv, Yang Shen, Dong Zhang, Bo Liu, Wei Zhao, Junyi Ju, Qingyi Zhu, Ke Wang, Ninghan Feng   +11 more
wiley   +1 more source

Advancements in DNA methylation technologies and their application in cancer diagnosis. [PDF]

Epigenetics
Yang Y, Wen X, Wang L.
europepmc   +1 more source

Steroid Studies. XII. On the Methylation of 3-Oxosteroids. (2).

, 1959
Kyosuke Tsuda, Shigeo Nozoe
openalex   +2 more sources

INFLUENCE OF BIOLOGICAL METHYLATION ON THE BIOSYNTHESIS OF MITOMYCIN A [PDF]

, 1964
E. J. Kirsch, J. D. KORSHALLA
openalex   +1 more source

From Code to Life: The AI‐Driven Revolution in Genome Editing

Advanced Science, EarlyView.
This review explores AI‐driven advancements in genome editing, focusing on CRISPR optimization, enhanced targeting precision, reduced off‐target effects, and novel tool design. It addresses ethical challenges, data biases, and highlights future prospects in precision medicine, agriculture, and synthetic biology.
Zhidong Li, Wasi Ullah Khan, Genxiang Bai, Chao Dong, Jungang Wang, Youpeng Zhang, Chong Wang, Hongbin Zhang, Wenyi Wang, Ming Luo, Fei Chen   +10 more
wiley   +1 more source

Identification of genetic and non-genetic modifiers of genomic imprinting through screening of imprinted DMR methylation in humans. [PDF]

Epigenetics Chromatin
Cecere F, Relator R, Levy M, Verma A, McConkey H, Mele BH, Pignata L, Giaccari C, D'Angelo E, Saha S, Saadat A, Sparago A, Angelini C, Cerrato F, Sadikovic B, Riccio A.   +15 more
europepmc   +1 more source

A Reductive Methylation of Quinones. [PDF]

, 1963
Jarl Gripenberg, Tapio Hase, Bertil Samuelsson, Jan Sjövall, Jon Munch‐Petersen   +4 more
openalex   +1 more source

Metabolic Stress‐Induced Choline Kinase α (CHKA) Activation in Endothelial Subpopulation Contributes to Diabetes‐Associated Microvascular Dysfunction

Advanced Science, EarlyView.
This study uncovers CHKA as a pivotal driver of vascular dysfunction in diabetic retinopathy and highlights its role in endothelial dysfunction through NAD⁺‐SIRT1‐Notch signaling. Single‐cell and functional analyses, combined with clinical and genetic validation, suggest CHKA as a promising therapeutic target for the prevention and treatment of ...
Ling Ren, Linyu Zhang, Yun Bai, Chang Huang, Xiaosa Li, Fanfei Ma, Wan Mu, Mudi Yao, Chang Jiang, Xiangjun Chen, Qin Jiang, Biao Yan   +11 more
wiley   +1 more source