Results 191 to 200 of about 1,069,555 (390)

Short double-stranded RNA induces transcriptional gene silencing in human cancer cells in the absence of DNA methylation

, 2005
Angela H. Ting, Kornel E. Schuebel, James G. Herman, Stephen B. Baylin   +3 more
openalex   +1 more source

A molecular mechanism for the enzymatic methylation of nitrogen atoms within peptide bonds [PDF]

, 2018
Haigang Song, Niels S. van der Velden, Sally L. Shiran, Patrick Bleiziffer, Christina Zach, Ramon Sieber, Aman S. Imani, Florian Krausbeck, Markus Aebi, Michael F. Freeman, Sereina Riniker, Markus Künzler, James H. Naismith   +12 more
openalex   +1 more source

DKK3 Initially Preserves Acinar Integrity Through MEK‐Fos Signaling, but Later Switches to an Oncogenic Role in Pancreatic Cancer

Advanced Science, EarlyView.
In pancreatic cancer, the protein DKK3 is found to play a complex role: it initially slows early tumor growth but later promotes tumor aggressiveness. DKK3 expression evolves during progression and drives cancer severity by orchestrating cellular and molecular signaling pathways.
Dharini Srinivasan, Elodie Roger, Lukas Perkhofer, Eleni Zimmer, Thomas F.E. Barth, Julia P. Mosler, Anna Härle, Stephanie E. Weissinger, Nadine T. Gaisa, Peter Möller, Nico Fischer, Chantal Allgöwer, J.‐Matthias Löhr, Dirk Grimm, Thomas Seufferlein, Stefan Liebau, Ninel Azoitei, Michael K. Melzer, Frank Arnold, Johann Gout, Alexander Kleger   +20 more
wiley   +1 more source

Repeat measures of DNA methylation in an inception cohort of firefighters [PDF]

, 2022
Jaclyn M. Goodrich, Alesia M. Jung, Melissa Furlong, Shawn C. Beitel, Sally R. Littau, John Gulotta, Darin Wallentine, Jefferey L. Burgess   +7 more
openalex   +1 more source

Establishing, maintaining and modifying DNA methylation patterns in plants and animals

Nature reviews genetics, 2010
Julie A. Law, S. Jacobsen
semanticscholar   +1 more source

Genome‐Wide by Lifetime Environment Interaction Studies of Brain Imaging Phenotypes

Advanced Science, EarlyView.
This study explores genome‐wide by lifetime environment interactions on brain imaging phenotypes. Gene‐environment interactions explain more phenotypic variance than main effects, pinpoint regulatory variants, and reveal exposure‐specific biological pathways.
Sijia Wang, Meiyun Wang, Peng Zhang, Jingliang Cheng, Longjiang Zhang, Wenzhen Zhu, Shijun Qiu, Zuojun Geng, Guangbin Cui, Yongqiang Yu, Weihua Liao, Xi‐Nian Zuo, Hui Zhang, Bo Gao, Xiaojun Xu, Tong Han, Zhenwei Yao, Quan Zhang, Feng Liu, Qiang Xu, Jiayuan Xu, Jilian Fu, Nana Liu, Yuan Ji, Jie Tang, Lining Guo, Mengge Liu, Xiaoxiao Xiao, Xiaoxuan Liu, Wei Li, Caihong Wang, Wei Wei, Dapeng Shi, Su Lui, Zhihan Yan, Feng Chen, Jing Zhang, Wen Shen, Yanwei Miao, Dawei Wang, Jia‐Hong Gao, Yunjun Yang, Kai Xu, Junfang Xian, Bing Zhang, Xiaochu Zhang, Zhaoxiang Ye, Le Yu, Wen Qin, Meng Liang, Chunshui Yu, the CHIMGEN Consortium   +51 more
wiley   +1 more source

DNA methylation and gene expression changes derived from assisted reproductive technologies can be decreased by reproductive fluids

, 2017
Sebastián Cánovas, Elena V. Ivanova, Raquel Romar, Soledad García-Martínez, Cristina Soriano‐Úbeda, Francisco Alberto García‐Vázquez, Heba Saadeh, Simon Andrews, Gavin Kelsey, Pilar Coy   +9 more
openalex   +1 more source

Psychological factors and DNA methylation of genes related to immune/inflammatory system markers: the VA Normative Aging Study [PDF]

, 2016
Daniel Kim, Laura D. Kubzansky, Andrea Baccarelli, David Sparrow, Avron Spiro, Letizia Tarantini, Laura Cantone, Pantel Vokonas, Joel Schwartz   +8 more
openalex   +1 more source

Evaluation of nanopore sequencing for epigenetic epidemiology: a comparison with DNA methylation microarrays [PDF]

, 2022
Robert J. Flynn, Sam Washer, Aaron R. Jeffries, Alexandria Andrayas, Gemma Shireby, Meena Kumari, Leonard C. Schalkwyk, Jonathan Mill, Eilís Hannon   +8 more
openalex   +1 more source

Inhibiting Liver‐Derived C3 Protein Rescues Anesthesia/Surgery‐Induced Cognitive Impairment, Synaptic Disorders, and Microglial Phagocytosis

Advanced Science, EarlyView.
This study provides evidence that anesthesia/surgery can induce the BBB breakdown and promote the release of hepatogenous C3 protein into the blood. This surgical dual factors ultimately drove C3 to cross the damaged BBB and selectively colocalize with C3aR in the hippocampus, which results in structural and functional injury of synapse, C3aR‐mediated ...
Qianqian Wu, Peilin Cong, Zhouxiang Li, Yuxin Zhang, Huanghui Wu, Qian Zhang, Yawei Li, Li Tian, Qingyuan Miao, Yinggang Zheng, Hui Zhang, Qian Chen, Enduo Feng, Xinyang Li, Zheping Chen, Dong‐Xin Wang, Xinwei Huang, Lize Xiong   +17 more
wiley   +1 more source