Results 191 to 200 of about 652,669 (356)

Cost-effective promoter methylation analysis via target long-read bisulfite sequencing: a case study in severe preterm birth. [PDF]

BMC Med Genomics
Pereyra S, Sardina A, Neumann R, May C, Sapiro R, Bertoni B, Cappetta M.   +6 more
europepmc   +1 more source

Nucleotides as an Anti‐Aging Supplementation in Older Adults: A Randomized Controlled Trial (TALENTs study)

Advanced Science, EarlyView.
The TALENTs randomized controlled trial evaluates the potential of nucleotides supplementation as an anti‐aging intervention in older adults. After 19 weeks, nucleotides supplementation significantly reduces DNA methylation age, suggesting a delay in epigenetic aging, and improves insulin sensitivity without severe adverse events.
Shuyue Wang, Lixia Song, Rui Fan, Qianqian Chen, Ruisheng Fu, Mei You, Yuxiao Wu, Meng Cai, Yong Li, Meihong Xu   +9 more
wiley   +1 more source

DNA Methylation: A Key Regulator in Male and Female Reproductive Outcomes. [PDF]

Life (Basel)
Adetunji AO, Owusu H, Adewale EF, Adesina PA, Xedzro C, Saliu TP, Islam S, Zhu Z, Morenikeji OB.   +8 more
europepmc   +1 more source

The Mass Spectra of Methyl Oleate, Methyl Linoleate, and Methyl Linolenate. [PDF]

Acta Chemica Scandinavica, 1959
Bo Hallgren, Ragnar Ryhage, Einar Stenhagen, R. Sömme, Einar Stenhagen, H. Palmstierna   +5 more
openaire   +2 more sources

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Science, 2017
Yimeng Yin, E. Morgunova, A. Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, P. Das, Teemu Kivioja, Kashyap Dave, F. Zhong, K. Nitta, Minna Taipale, A. Popov, P. Ginno, Silvia Domcke, Jian Yan, D. Schübeler, C. Vinson, J. Taipale   +18 more
semanticscholar   +1 more source

Targeting Intratumoral Copper Inhibits Tumor Progression via p62‐Mediated EZH2 Degradation and Potentiates Anti‐PD‐1 Immunotherapy in Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
The authors find that by targeting intratumoral copper, they can enhance p62‐mediated ubiquitination of EZH2 at the Ub‐K63 site by suppressing copper binding to SMURF2, an E3 ligase of EZH2, leading to its autophagic degradation. This mechanism suppressed OSCC progression and potentiated anti‐PD‐1 immunotherapy, highlighting a potential new therapeutic
Xiaohu Lin, Wanling Chen, Bo Li, Zhang Zhao, Zhonglin Yu, Xu‐Yun Zhao, Xuan Zhou, Zhien Feng, Chengzhong Lin, Wei Cao   +9 more
wiley   +1 more source

Overweight and POMC methylation: epigenetic associations with adolescent depression. [PDF]

BMC Psychiatry
Ye Y, Hu JH, Xiao XY, Ji T, Wang F, Jia FJ, Hou CL.   +6 more
europepmc   +1 more source

Accounting for ALA Natural Mutations Enhances the Efficiency of Graphene Oxide Nanopriming in Bar‐Modified Arabidopsis

Advanced Science, EarlyView.
Nanopriming enhances plant resilience to environmental challenges; however, its effectiveness across diverse genetic backgrounds, including genetic modifications and natural variations, remains uncertain. These findings demonstrate that nanopriming improves efficacy when natural genetic variations are considered, particularly in genetically modified ...
Yining Wu, Rui Sun, Yueting Cui, Jun Qiao, Chengdong Zhang   +4 more
wiley   +1 more source

Epigenetic age acceleration in peripheral blood correlates with brain-MRI age acceleration. [PDF]

Brain
Sant'Anna Barbosa Ferreira P, van Dongen J, den Braber A, Boomsma DI, de Geus EJC, van 't Ent D.   +5 more
europepmc   +1 more source

THE CONSTITUTION OF A SYNTHETIC GLUCAN: II. METHYLATION STUDIES

, 1963
Guy G.S. Dutton, A. M. Unrau
openalex   +1 more source