Results 191 to 200 of about 443,290 (339)

High‐Throughput Proteoform Imaging for Revealing Spatial‐Resolved Changes in Brain Tissues Associated with Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
High‐throughput proteoform imaging (HTPi) is established by combining matrix‐assisted laser desorption ionization mass spectrometry imaging and high‐sensitivity region‐specific top‐down proteomic analysis. HTPi enables the generation of annotated proteoform images with exceptional precision, high throughput, and deep coverage, showing distinct spatial ...
Yue Sun   +8 more
wiley   +1 more source

Corrigendum: Development and validation of a prognostic nomogram based on DNA methylation-driven genes for patients with ovarian cancer

open access: yesFrontiers in Genetics, 2022
Min Zhou   +7 more
doaj   +1 more source

The Mass Spectra of Methyl Oleate, Methyl Linoleate, and Methyl Linolenate. [PDF]

open access: yesActa Chemica Scandinavica, 1959
Bo Hallgren   +5 more
openaire   +2 more sources

ALKBH3‐Mediated M1A Demethylation of METTL3 Endows Pathological Fibrosis:Interplay Between M1A and M6A RNA Methylation

open access: yesAdvanced Science, EarlyView.
RNA modification is crucial in fibrosis diseases, but the role of m1A modification remains elusive. This study reveals that ALKBH3, an m1A demethylase, drives skin fibrosis by reshaping m6A RNA modification and stabilizing COL1A1 and FN1 mRNAs through METTL3, uncovering a crosstalk between m1A and m6A methylation in pathological events.
Liying Tu   +9 more
wiley   +1 more source

Genome-wide DNA methylation patterns in Daphnia magna are not significantly associated with age. [PDF]

open access: yesEpigenetics Chromatin
Liu R   +4 more
europepmc   +1 more source

Chemical Studies of Histone Methylation

open access: hybrid, 1969
Edward L. Gershey   +3 more
openalex   +1 more source

PRMT1‐Mediated SWI/SNF Complex Recruitment via SMARCC1 Drives IGF2BP2 Transcription to Enhance Carboplatin Resistance in Head and Neck Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
PRMT1 drives carboplatin resistance and tumor progression in head and neck squamous cell carcinoma (HNSCC) through a novel, methyltransferase‐independent mechanism. It recruits the SWI/SNF complex to activate IGF2BP2, promoting tumor growth and carboplatin resistance. PBX2 upregulates PRMT1, reinforcing this pathway. This study uncovers a non‐catalytic
Shixian Liu   +22 more
wiley   +1 more source

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