Results 161 to 170 of about 16,619 (178)

MicroRNA-767-5p promotes metastasis but improves chemotherapeutic and radiotherapeutic sensitivity of osteosarcoma. [PDF]

BMC Cancer
Luo X, Dai X, Wei Q, Tan X, Wang S, Xiao H, Yao X, Deng Y, Zhong Z.   +8 more
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The mitogenic and collagen biosynthesis stimulating activities in the serum of rats with the methylcholanthrene induced sarcoma.

, 1993
Jerzy Pałka, K Sobolewski, E Bańkowski
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Enhancement of microsomal drug hydroxylation and glucuronidation in rat liver by phenobarbital and 3-methylcholanthrene in combination.

Acta Pharmacologica et Toxicologica, 2009
: Both 3-methylcholanthrene and phenobarbital increased the 0-demethylation of p-nitroanisole in rat liver microsomes (9-fold and 6-fold, respectively), whereas 3-methylcholanthrene alone was able to enhance the aryl hydrocarbon hydroxylase activity (13 ...
H. Vainio, A. Aitio
semanticscholar   +1 more source

A comparative study on drug hydroxylation and glucuronidation in liver microsomes of phenobarbital and 3-methylcholanthrene treated rats.

Acta Pharmacologica et Toxicologica, 2009
The treatment of hepatic microsomes with phospholipase A or phospholipase C decreased the drug hydroxylase activity. The exception was the aryl hydrocarbon hydroxylase in hepatic microsomes from 3-methylcholanthrene pre-treated rats.
H. Vainio, O. Hänninen
semanticscholar   +1 more source

Two unique CYP1 genes are expressed in response to 3-methylcholanthrene treatment in rainbow trout.

Archives of Biochemistry and Biophysics, 1994
In animals, exposure to polyaromatic hydrocarbons (PAHs) such as 3-methylcholanthrene (3-MC) is known to induce the expression of two unique cytochrome P450 genes, CYP1A1 and CYP1A2.
A. Berndtson, T. T. Chen
semanticscholar   +1 more source

Neoplastic transformation of SV40-immortalized human urinary tract epithelial cells by in vitro exposure to 3-methylcholanthrene.

Carcinogenesis, 1988
Normal human urinary tract epithelial cells (HUC) were neoplastically transformed in vitro using a step-wise strategy. First, a partially transformed non-virus-producing cell line was obtained after infection of HUC with simian virus 40 (SV40). This cell
C. Reznikoff, L. Loretz, B. Christian, Shi-qi Wu, L. Meisner   +4 more
semanticscholar   +1 more source

Identification of a novel P450 expressed in rat lung: cDNA cloning and sequence, chromosome mapping, and induction by 3-methylcholanthrene.

Biochemistry, 1989
A novel P450 cDNA was isolated from a rat lung lambda gt11 library by hybridization with the rat P450 IIB1 cDNA probe. The cDNA-deduced amino acid sequence of this clone was 71% and 73% similar to rat IIA1 and IIA2 P450s; it was, therefore, designated ...
S. Kimura, C. Kozak, F. Gonzalez
semanticscholar   +1 more source

Analysis of antigenic heterogeneity within individual 3-methylcholanthrene-induced mouse sarcomas.

Journal of the National Cancer Institute, 1970
A method of establishing sublines by trocar transplantation in vivo was used to analyze possible cellular heterogeneity with regard to tumor-specific antigens in individual methylcholanthrene-induced sarcomas.
R. Prehn
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Selective induction of two different molecular species of cytochrome P-450 by phenobarbital and 3-methylcholanthrene.

Journal of Biochemistry (Tokyo), 1981
Two forms of cytochrome P-450, P-450PB and P-450MC, were purified to homogeneity from the liver microsomes of phenobarbital (PB)-treated and 3-methylcholanthrene (MC)-treated rats, respectively. Rabbit antibodies against P-450PB and P-450MC were prepared
N. Harada, T. Omura
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