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Methyldopa and Hypertension [PDF]
S R, WHITTAKER, R, ROBINSON, A W, STOTT
openaire +4 more sources
Methyldopa is the main antihypertensive drug widely used in pregnant women with hypertensive disorder. It lowers blood pressure in pre-eclampsia by affecting a2-adrenoreceptors in central nervous system.
Dina Ratna Juwita +2 more
doaj +2 more sources
Hypertension in pregnancy including chronic hypertension with or without pre-eclampsia, gestational hypertension increases maternal and infant mortality significantly.
Mayna Mayna +4 more
doaj +3 more sources
Background: Hypertensive disorders represent the most common medical complication of pregnancy, with a reported incidence of 6-10% and accounts for 15% of maternal mortality.
Mary Rohini Pentareddy +5 more
openalex +3 more sources
Enhancing methyldopa solubility via green supercritical fluid techniques using ethanol co-solvent [PDF]
Alotaibi H +8 more
europepmc +2 more sources
Spectrophotometric Determination of Methyldopa in Pure and Pharmaceutical Preparations by the Oxidative Coupling Reaction with 1, 5-Diaminonaphthalene in the Presence of Ammonium Ceric (IV) Nitrate [PDF]
Oxidative coupling reactions are one of the significant methods used in the estimation of certain drugs in pharmaceutical formulations. This study describes the development of a fast and sensitive spectroscopic method considering the determination of ...
Noor Mansoor Ghaib Allah +2 more
doaj +1 more source
Antihypertensive therapy for pregnancy hypertension and implications for fetal and neonatal heart rate monitoring: A systematic review of randomized trials and observational studies. [PDF]
Trials are mostly reassuring regarding antihypertensive effects on fetal (FHR) or neonatal heart rate (neoHR), but observational studies raise concerns about beta‐blockers, particularly the alpha/beta‐blocker labetalol. Clinicians should ascribe adverse fetal or neonatal heart rate effects to evolving underlying placental dysfunction or newborn illness,
Ganeshamoorthy A +9 more
europepmc +2 more sources
Antihypertensive drugs are among the most prescribed drugs during pregnancy. Methyldopa, labetalol, and nifedipine have been perceived safe to use during pregnancy and are therefore recommended in international guidelines for treatment of hypertension ...
Dylan van de Vusse +6 more
semanticscholar +1 more source
Design of sensitive electrochemical sensor as the analytical tool for methyldopa in drug and biological samples [PDF]
In this work, an electrochemical sensor based on carbon paste electrode modified with Au nanoparticle and 1-methyl-3-octylimidazolium chloride was fabricated as a sensor for determination of methyldopa.
Maryam Abbasghorbani
doaj +1 more source

