Results 51 to 60 of about 15,220 (247)
Methodical approaches to bioassay of substances containing unstable functional groups [PDF]
, 2018 This article describes the method development approaches for bioassay of substances containing unstable functional groups and forming unstable metabolites using the example of mycophenolic acid, methyldopa and mebeverine ...
Dzhurko, Yu. A. +4 more
core +2 more sources
Analytical Investigation of the Possible Chemical Interaction of Methyldopa with Some Reducing Carbohydrates Used as Pharmaceutical Excipients [PDF]
Advanced Pharmaceutical Bulletin, 2018 Purpose: Assessment of drug substance and excipients compatibility is an important issue during pre-formulation studies as well as the quality control of pharmaceutical dosage forms.
Mohammad Reaz Siahi +2 more
doaj +1 more source
mBio, 2022 Transmission of HIV across the mucosal surface of the female reproductive tract to engage subepithelial CD4-positive T cells is not fully understood. Cervical epithelial cells express complement receptor 3 (CR3) (integrin αMβ2 or CD11b/CD18).
Christopher J. Day +7 more
doaj +1 more source
Interaction Between NOS3 and HMOX1 on Antihypertensive Drug Responsiveness in Preeclampsia [PDF]
Revista Brasileira de Ginecologia e Obstetrícia, 2020 Objective We examined the interaction of polymorphisms in the genes heme oxygenase- 1 (HMOX1) and nitric oxide synthase (NOS3) in patients with preeclampsia (PE) as well as the responsiveness to methyldopa and to total antihypertensive therapy. Methods
Valeria Cristina Sandrim +8 more
doaj +1 more source
Movement Disorders Clinical Practice, EarlyView.ABSTRACT Background Levodopa‐carbidopa intestinal gel infusion (LCIG) is an effective therapy for advanced Parkinson's disease (PD). Opicapone (OPC) is an enzyme inhibitor that enhances the bioavailability of levodopa in the brain. Objectives This study evaluates the effect of Opicapone addition in PD‐LCIG patients, assessing its impact on motor ...
Fabiana Colucci +9 more
wiley +1 more source
Química Nova, 2015 An enzymatic spectrophotometric method for the determination of methyldopa in a dissolution test of tablets was developed using peroxidase from radish (Raphanus sativus).
Natielle Gianine Bueno +1 more
doaj +1 more source
Drug Analytical Research, 2021 A new and direct colorimetric method has been established for the determination of catecholamine (methyldopa, MD) in both pure form and in pharmaceutical formulations.
Safwan Ashour
doaj +1 more source
The Postural Tachycardia Syndrome (POTS): Pathophysiology, Diagnosis & Management [PDF]
, 2006 Postural tachycardia syndrome (POTS), characterized by orthostatic tachycardia in the absence of orthostatic hypotension, has been the focus of increasing clinical interest over the last 15 years 1. Patients with POTS complain of symptoms of tachycardia,
Raj, Satish R
core +1 more source
Movement Disorders Clinical Practice, EarlyView.Abstract Background Pregnancy after a Parkinson's diagnosis presents complex challenges. Due to the paucity of literature, there is no evidence‐based guidelines and protocols for preconception care, management of pregnancy, childbirth and the postpartum period in women with early‐onset Parkinson's disease (PD).
Alexander C. Lehn +18 more
wiley +1 more source
Rapid healing of a patient with dramatic subacute combined degeneration of spinal cord: a case report [PDF]
, 2017 Background: Prevalence of cobalamin deficiency is high especially in older patients and an immediate therapy start is necessary to prevent irreversible neurological damages. Unfortunately, the diagnosis of cobalamin deficiency is difficult and at present,
Roessler, Florian C., Wolff, Stephanie
core +1 more source