Results 11 to 20 of about 13,481 (184)

Evaluation of Methylenetetrahydrofolate Reductase (MTHFR) Activity and the Levels of Homocysteine and Malondialdehyde (MDA) in the Serum of Women With Preeclampsia

Clinical and Experimental Hypertension, 2020
Background Methylenetetrahydrofolate reductase (MTHFR) has a key role in converting homocysteine to methionine so its deficiency might cause homocysteine accumulation and arterial destruction.
Iraj Khodadadi, Sahar Mazloomi, Gholamreza Shafiee   +2 more
exaly   +2 more sources

METHYLENETETRAHYDROFOLATE REDUCTASE POLYMORPHISMS IN PREECLAMPSIA AND THE HELLP SYNDROME

Hypertension in Pregnancy, 2000
To investigate the prevalence of the 677 (C --> T) and 1298 (A --> C) polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene in our preeclamptic population. For a summary estimation of the risk of the 677 (C --> T) polymorphism for preeclampsia, we also performed a meta-analysis on four previously published case-control studies to which ...
Petra L.M. Zusterzeel, Willy Visser, Henk J. Bolm, Wilbert H.M. Peters, Sandra G. Heil, Eric A.P. Steegers, E. A.P. Steegers   +6 more
openaire   +6 more sources

Assessment of Methylenetetrahydrofolate Reductase Gene Polymorphism in Diabetic Peripheral Neuropathy [PDF]

Zagazig University Medical Journal, 2022
Background: Among patients with diabetic polyneuropathy, the status of folic acid, homocysteine, and nerve conduction studies (NCS) variations has been associated with methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms.
amal Fawzy, Azza Abd El-Fatah, abdullah abdulhamid   +2 more
doaj   +1 more source

Is enoxaparin necessary to prevent adverse pregnancy outcomes in methylenetetrahydrofolate reductase polymorphism positive recurrent pregnancy loss cases?

Medicine Science, 2020
The association between methylenetetrahydrofolate reductase polymorphism and recurrent pregnancy loss is still under debate. Moreover, the use of enoxaparin to prevent adverse pregnancy outcomes is controversial in these patients. We aimed to analyse the
Hakan Sager, Muhammed Emin Sancak, Burcu Dincgez Cakmak, Sonay Oztas, Begum Uzsezer, Ebru Inci Coskun   +5 more
doaj   +1 more source

Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism in psoriasis in southern Turkey [PDF]

Anais Brasileiros de Dermatologia, 2016
: Background: Psoriasis is a multigenic and multifactorial dermatological disease linked to cardiovascular diseases. Increased levels of homocysteine in patients with psoriasis have been demonstrated in many studies.
Muzeyyen Izmirli, Bilge Bulbul Sen, Eminenur Rifaioglu, Bulent Gogebakan, Ozgur Aldemir, Tuba Sen, Ozlem Ekiz, Davut Alptekin   +7 more
doaj   +2 more sources

The correlation between methylenetetrahydrofolate reductase gene 677C > T polymorphism and fetal congenital defects: A meta-analysis

Pteridines, 2020
Objective To investigate the correlation between the methylenetetrahydrofolate reductase (MTHFR) gene 677C> T polymorphism and fetal congenital defects.
Li Dexia, Wang Enxia, Gao Xia, Li Ping
doaj   +1 more source

Cystathionine β-synthase and methylenetetrahydrofolate reductase mutations in Mexican individuals with hyperhomocysteinemia

SAGE Open Medicine, 2020
Background: Hyperhomocysteinemia, a thrombotic risk factor, may have several causes. Among the genetic causes of hyperhomocysteinemia, there are polymorphisms in the enzymes methylenetetrahydrofolate reductase (C677T) and cystathionine β-synthase (C699T,
Anahi Guadalupe Figueroa-Torres, Lisneth Osiris Matias-Aguilar, Erika Coria-Ramirez, Edmundo Bonilla-Gonzalez, Humberto Gonzalez-Marquez, Isabel Ibarra-Gonzalez, Jose Rubicel Hernandez-Lopez, Jesus Hernandez-Juarez, Victor Manuel Dominguez-Reyes, Irma Isordia-Salas, Abraham Majluf-Cruz   +10 more
doaj   +1 more source

The Frequency of Some Thrombophilic Mutations in Eastern Turkey

Eurasian Journal of Medicine, 2019
Objective: Factor V / Factor II / Methylenetetrahydrofolate reductase, gene polymorphisms are closely associated with thrombophilia. Regional frequencies of these mutations may show a characteristic state.
Nurinnisa Ozturk, Ebubekir Bakan, Mehmet Ali Gul, Nuri Bakan, Engin Sebin, Ahmet Kiziltunc   +5 more
doaj   +1 more source

Methylenetetrahydrofolate reductase gene polymorphism is not related to the risk of ischemic cerebrovascular disease in a Brazilian population Polimorfismo no gene de metilenetetrahidrofolato redutase não está relacionado com o risco de doença cerebrovascular isquêmica em uma população brasileira

Clinics, 2007
PURPOSE: Data are conflicting concerning the risk for ischemic stroke associated with a common polymorphism in the gene encoding 5,10-methylenetetrahydrofolate reductase C677T, which predisposes carriers to hyperhomocysteinemia.
Samuel Katsuyuki Shinjo, Sueli Mieko Oba-Shinjo, Roseli da Silva, Keila Cardoso Barbosa, Fabio Yamamoto, Milberto Scaff, Suely Kazue Nagahashi Marie   +6 more
doaj   +1 more source

The Relationship Between Methylation Defects and Different Genetic Disorders: Two Case Reports

Gynecology Obstetrics & Reproductive Medicine, 2016
5, 10-methylenetetrahydrofolate reductase (MTHFR) is a coding gene, for a key enzyme in methionine-homocysteine and folate metabolism. This pathway has been associated with gene specific DNA hypo and hypermethylation as a result of gene switching on or ...
Emine Aydın, Ahmet Cevdet Ceylan, Mehmet Sinan Beksaç   +2 more
doaj   +1 more source