Results 71 to 80 of about 123 (115)

Acylierungsreaktionen an Methylhydrazin

Archiv der Pharmazie, 1971
AbstractMethylhydrazin wird mit Dimethyl‐ und Diäthylcarbonat in 1‐ und in 2‐Stellung acyliert, weitere Behandlung mit Isocyansäureestern führt zu Acylsemicarbaziden, die zu Derivaten des Urazols cyclisiert werden. Bei der Formylierung mit Methyl‐ und Äthylformiat wurde dagegen nur 1‐Formyl‐1‐methylhydrazin gefaßt und mit Carbonyl‐Verbindungen in ...
G. Zinner, U. Gebhardt
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Cytostatischer Wirkungsmechanismus der Methylhydrazine

Experientia, 1964
Cytostatic active methylhydrazine derivatives split off formaldehyde after mild dehydrogenation with potassium hexacyanoferrate (III). It is suggested that the primary formedazomethines andN-hydroxymethylderivatives participate in cytostatic efficacy by their alkylating ability (aminomethylation).
G. Weitzel, F. Schneider, Anna-Maria Fretzdorff   +2 more
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ChemInform Abstract: ACYLIERUNGSRK. AN METHYLHYDRAZIN

Chemischer Informationsdienst. Organische Chemie, 1971
AbstractMethylhydrazin (I) reagiert mit Dimethyl‐ oder Diäthylcarbonat (II) in 15 bzw. 27%iger Ausbeute zu den 1‐Alkoxycarbony1‐1‐methylhydrazinen (III) und in 27 bzw. 39%iger Ausbeute zu den 1‐Methyl‐2‐alkoxycarbonylhydrazinen (IV), die sich durch fraktionierte Kristallisation trennen lassen.
G. ZINNER, U. GEBHARDT
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Substituted 2-Aminobenzoyl Derivatives of Methylhydrazine

Synthetic Communications, 1976
Abstract Acylation of arylhydrazines gives acyl 2-arylhydrazides1 while acylation of alkylhydrazines yields either 1-alkyl or 2-alkylhydrazides depending on the choice of acylating agent. Earlier examples of the variability of acylation sites in the alkylhydrazines2,3 were systematically reinvestigated by Hinman4 and Moore5 who established that esters,
Robert W. Leiby, Ned D. Heindel
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Ueber das Methylhydrazin

Justus Liebigs Annalen der Chemie, 1889
Von den Hydrazinen der Fettreihe sind bisher die Monoathyl-, Diathyl- und Dimethylverbindungen naher untersucht; dagegen ist die einfachste dieser Basen, das Methylhydrazin, noch nicht erhalten worden.
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Reaction of pyrylium salts with methylhydrazine

Journal of the Chemical Society D: Chemical Communications, 1970
The reaction of (1; R = Ph or Me) with methyl-hydrazine leads to a variety of products, (2e), (3d), (3e), (5), (6a), and (7), depending on the selected pyrylium salt and reaction conditions.
Victor Snieckus, Gordon Kan
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Mechanisms and kinetics of hydrogen abstraction of methylhydrazine and deuterated methylhydrazine with H/D atoms

Theoretical Chemistry Accounts, 2012
The mechanisms of multi-channel reactions (1) CH3NHNH2 + H → products (R1) and (2) (CH3)2NNH2 + H → products (R2) have been investigated, and the dynamic properties are studied by using the dual-level direct dynamics method. The electronic structures and energies of the stationary points are calculated by the combination of various methods and basis ...
Wang, Li, Zhao, Yuan, Wen, Jinmiao, Zhang, Jinglai   +3 more
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Initial experiences with methylhydrazine, a new cytotoxic agent

Clinical Radiology, 1966
The authors present their results using methylhydrazine (‘Ro 4-6467’, ‘Natulan’) in the treatment of 40 patients with malignant disease. The progress of 29 patients could be adequately assessed. Remissions occurred frequently in patients with Hodgkin's disease and some solid tumours also showed a response.
T W, Backhouse, K, Sicher
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The Treatment of Lymphomas with Vincaleukoblastine and Methylhydrazine

Acta geneticae medicae et gemellologiae, 1968
SummaryResults of Chemotherapic treatment in Hodgkin's disease are reported. 23 cases were treated by Vincaleucoblastine, 19 by Methylhydrazine, and 12 by both drugs. With VLB we obtained 6 complete remissions, 12 partial remissions and 5 failures; with MH the remissions were 9 complete, 4 partial and 6 failures.
E, Anlesio, A, Calciati, V, Caramello
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Reaction of methylhydrazine with dimethyl chlorothiophosphate

Journal of the Chemical Society, Dalton Transactions, 1994
The reaction of 2 equivalents of methylhydrazine with 1 equivalent of (MeO)2P(S)Cl at 0 °C produced the phosphorus hydrazide (MeO)2P(S)NMeNH21 in good yield. However, at 25 °C a mixture of three products was obtained according to 1H and 31P NMR spectra. The pure individual components were separated by column chromatography.
Przemyslaw Lusiak, Prahlad R. Singh, Kattesh V. Katti   +2 more
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