Results 91 to 100 of about 5,012,650 (270)

Trends in resource utilization for new‐onset psychosis hospitalizations at children's hospitals

open access: yesJournal of Hospital Medicine, Volume 20, Issue 7, Page 710-726, July 2025.
Abstract Background Children with new‐onset psychosis often require hospitalization for medical evaluation. Objectives The goal of this study was to assess variations in the management of children with new‐onset psychosis and characterize trends in resource utilization.
Ankita Gupta   +8 more
wiley   +1 more source

Screening for Life: Perspectives From Adult Metabolic Specialists on Newborn Screening for Inherited Metabolic Diseases

open access: yesJournal of Inherited Metabolic Disease, Volume 48, Issue 4, July 2025.
ABSTRACT The number of inherited metabolic diseases (IMDs) in newborn screening (NBS) programs has increased significantly in the past decades. For some of the IMDs included in NBS (e.g., tyrosinemia type I), there are clear and substantial health benefits of NBS, while for others (e.g., very long chain acyl CoA dehydrogenase deficiency and 3 ...
Mirjam Langeveld   +9 more
wiley   +1 more source

The Reaction of Methylmalonic Acid with Aldehydes

open access: yesNippon kagaku zassi, 1962
π-プチルアルデヒド,π-ヘプタアルデヒド,およびρ-ニトロベンズァルデヒドをメチルマロン酸とピリジンまたはトリェチルアミンの存在で反応させた。反応は脱炭酸のみをともない,α-メチル-β-オキシカルボン酸が生成された。このオキセ酸を85%硫酸中でラクトン化させてα-メチル-γ-カプロラクトンおよび-γ-η-ノナラクトンが得られた。
openaire   +2 more sources

Expert Perspective: Hematologic Malignancies and Vasculitis

open access: yes
Arthritis &Rheumatology, EarlyView.
Michelle L. Robinette, Hetty E. Carraway
wiley   +1 more source

Late‐Onset Multiple Acyl‐CoA Dehydrogenase Deficiency (MADD): A Case Report With a Complex Biochemical Profile

open access: yesJIMD Reports, Volume 66, Issue 4, July 2025.
ABSTRACT Three clinical entities of multiple acyl‐CoA dehydrogenase deficiency (MADD, OMIM#231680) can be differentiated: two severe neonatal forms and one later‐onset form that can manifest in adulthood. The latter typically presents with muscle‐related symptoms, such as exercise intolerance and muscle weakness, with an increase in all chain‐length ...
Romain Penicaud   +8 more
wiley   +1 more source

Methylmalonic acidemia with recurrent hemophagocytic lymphohistiocytosis: a case report and review of the literature

open access: yesBMC Pediatrics
Background Methylmalonic acidemia is a rare autosomal recessive disorder of propionate catabolism characterized by the accumulation of propionic acid and methylmalonic acid caused by methylmalonyl-CoA mutase deficiency.
Fumiya Yamashita   +9 more
doaj   +1 more source

Liquid chromatography-tandem mass spectrometry - Application in the clinical laboratory [PDF]

open access: yes, 2003
This review provides a concise survey of liquid chromatography tandem mass spectrometry (LCTMS) as an emerging technology in clinical chemistry. The combination of two mass spectrometers with an interposed collision cell characterizes LCTMS as an ...
Ford RE   +7 more
core   +1 more source

Enhancing Functional Protein Design Using Heuristic Optimization and Deep Learning for Anti‐Inflammatory and Gene Therapy Applications

open access: yesProteins: Structure, Function, and Bioinformatics, Volume 93, Issue 7, Page 1238-1256, July 2025.
ABSTRACT Protein sequence design is a highly challenging task, aimed at discovering new proteins that are more functional and producible under laboratory conditions than their natural counterparts. Deep learning‐based approaches developed to address this problem have achieved significant success.
Ayşenur Soytürk Patat   +1 more
wiley   +1 more source

Vitamin B12 measurements across neurodegenerative disorders. [PDF]

open access: yes, 2020
Background:Vitamin B12 deficiency causes a number of neurological features including cognitive and psychiatric disturbances, gait instability, neuropathy, and autonomic dysfunction. Clinical recognition of B12 deficiency in neurodegenerative disorders is
Christine, Chadwick W   +3 more
core  

B vitamins and cognitive performance in older adults: Review [PDF]

open access: yes, 2013
A copious amount of scientific scrutiny has been dedicated to documenting typical and atypical human ageing, with a substantial body of work focusing upon the impact of lifestyle choices.
Reay, Jonathon   +2 more
core   +3 more sources

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