Microbial phenotypic heterogeneity in response to a metabolic toxin: Continuous, dynamically shifting distribution of formaldehyde tolerance in Methylobacterium extorquens populations. [PDF]
PLoS Genetics, 2019 While microbiologists often make the simplifying assumption that genotype determines phenotype in a given environment, it is becoming increasingly apparent that phenotypic heterogeneity (in which one genotype generates multiple phenotypes simultaneously ...
Jessica A Lee +7 more
doaj +2 more sources
Poly(3-hydroxybutyrate) production in an integrated electromicrobial setup: Investigation under stress-inducing conditions. [PDF]
PLoS ONE, 2018 Poly(3-hydroxybutyrate) (PHB), a biodegradable polymer, can be produced by different microorganisms. The PHB belongs to the family of polyhydroxyalkanoate (PHA) that mostly accumulates as a granule in the cytoplasm of microorganisms to store carbon and ...
Israa Salem Al Rowaihi +6 more
doaj +7 more sources
Metabolomics Revealed an Association of Metabolite Changes and Defective Growth in Methylobacterium extorquens AM1 Overexpressing ecm during Growth on Methanol. [PDF]
PLoS ONE, 2016 Methylobacterium extorquens AM1 is a facultative methylotroph capable of growth on both single-carbon and multi-carbon compounds. The ethylmalonyl-CoA (EMC) pathway is one of the central assimilatory pathways in M.
Jinyu Cui +6 more
doaj +2 more sources
Expanding on the ability of trivalent actinides to support microbial alcohol metabolism in evolved methylotrophic bacterium [PDF]
Communications ChemistryThe 4 f elements, known as the lanthanides, have only recently been recognized as biologically essential metals. These elements can be found in the active site of certain alcohol dehydrogenase (ADH) enzymes, which are used by methylotrophic bacteria to ...
Joshua J. Woods +7 more
doaj +2 more sources
Functional diversity of isoprenoid lipids in Methylobacterium extorquens PA1 [PDF]
Molecular Microbiology, 2021 AbstractHopanoids and carotenoids are two of the major isoprenoid‐derived lipid classes in prokaryotes that have been proposed to have similar membrane ordering properties as sterols. Methylobacterium extorquens contains hopanoids and carotenoids in their outer membrane, making them an ideal system to investigate the role of isoprenoid lipids in ...
Sandra Rizk +8 more
+10 more sources
Characterization of a Novel Fe2+ Activated Non-Blue Laccase from Methylobacterium extorquens. [PDF]
Int J Mol Sci, 2022 Herein, a novel laccase gene, Melac13220, was amplified from Methylobacterium extorquens and successfully expressed in Escherichia coli with a molecular weight of approximately 50 kDa. The purified Melac13220 had no absorption peak at 610 nm and remained silent within electron paramagnetic resonance spectra, suggesting that Melac13220 belongs to the ...
Ainiwaer A, Liang Y, Ye X, Gao R.
europepmc +3 more sources
Methylobacterium extorquens: methylotrophy and biotechnological applications [PDF]
Applied Microbiology and Biotechnology, 2014 Applied Microbiology and Biotechnology, 99 (2)
Andrea M. Ochsner +4 more
openaire +3 more sources
Use of rare-earth elements in the phyllosphere colonizer Methylobacterium extorquens PA1. [PDF]
Mol Microbiol, 2019 SummaryUntil recently, rare‐earth elements (REEs) had been thought to be biologically inactive. This view changed with the discovery of the methanol dehydrogenase XoxF that strictly relies on REEs for its activity. Some methylotrophs only contain xoxF, while others, including the model phyllosphere colonizer Methylobacterium extorquens PA1, harbor this
Ochsner AM +6 more
europepmc +5 more sources
Population heterogeneity in Methylobacterium extorquens AM1 [PDF]
Microbiology, 2009 Heterogeneity of cells within exponentially growing populations was addressed in a bacterium, the facultative methylotroph Methylobacterium extorquens AM1. A transcriptional fusion between a well-characterized methanol-inducible promoter (PmxaF ) and gfpuv was used with flow cytometry to analyse the distribution of ...
Tim J, Strovas, Mary E, Lidstrom
openaire +2 more sources
Comparative Binding Studies of the Chelators Methylolanthanin and Rhodopetrobactin B to Lanthanides and Ferric Iron. [PDF]
ChembiochemThe synthesis and the investigation of the lanthanide (Ln) and Fe‐binding properties of the putative lanthanophore methylolanthanin (MLL) and the siderophore rhodopetrobactin B (RPB B) are reported. While both chelators bind Lns, they unexpectedly precipitate with Lns under biologically relevant conditions and thereby challenge the proposed classic ...
Gutenthaler-Tietze SM +9 more
europepmc +2 more sources