Results 131 to 140 of about 1,130 (159)
Guidance for engineering of synthetic methylotrophy based on methanol metabolism in methylotrophy
RSC Advances, 2017 Methanol represents an attractive non-food raw material in biotechnological processes from an economic and process point of view. It is vital to elucidate methanol metabolic pathways, which will help to genetically construct non-native methylotrophs.
Fengxue Xin, Min Jiang, Weiliang Dong
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Synthetic Methylotrophy: A Practical Solution for Methanol-Based Biomanufacturing
Trends in Biotechnology, 2020The increasing availability and affordability of natural gas has renewed interest in using methanol for bioproduction of useful chemicals. Engineering synthetic methylotrophy based on natural or artificial methanol assimilation pathways and genetically tractable platform microorganisms for methanol-based biomanufacturing is drawing particular attention.
Ping Zheng, Jibin Sun, Yu Wang
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Synthetic Methylotrophy: Past, Present, and Future
, 2018 Methane and methanol are regarded as alternative and highly attractive nonfood raw materials for the biotechnology sector. The supply of methane and methanol comes from both fossil and renewable resources, rendering them flexible and sustainable raw materials. Reduced one-carbon (C1) compounds are used by specialized groups of microorganisms, i.e., the
Julia A Vorholt +2 more
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Transposon Sequencing Uncovers an Essential Regulatory Function of Phosphoribulokinase for Methylotrophy [PDF]
Current Biology, 2017 Methylotrophy is the ability of organisms to grow at the expense of reduced one-carbon compounds, such as methanol or methane. Here, we used transposon sequencing combining hyper-saturated transposon mutagenesis with high-throughput sequencing to define the essential methylotrophy genome of Methylobacterium extorquens PA1, a model methylotroph.
Matthias Christen +2 more
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Genome-guided insight into the methylotrophy of Paracoccus aminophilus JCM 7686 [PDF]
Frontiers in Microbiology, 2015 Paracoccus aminophilus JCM 7686 (Alphaproteobacteria) is a facultative, heterotrophic methylotroph capable of utilizing a wide range of C1 compounds as sole carbon and energy sources. Analysis of the JCM 7686 genome revealed the presence of genes involved in the oxidation of methanol, methylamine, dimethylamine, trimethylamine, N,N-dimethylformamide ...
Daniel Wibberg +2 more
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Regulation of methylotrophy in Paracoccus denitrificans
Advances in Microbial PhysiologyParacoccus denitrificans is a long-established model organism for studies of methylotrophy, the use of one-carbon compounds as sources of energy and carbon. P. denitrificans can use methanol and methylamine as growth substrates, oxidizing both to formaldehyde in the periplasm.
Stephen Spiro
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Metals and methylotrophy: Via global gene expression studies
2021A number of minerals, such as copper, cobalt, and rare earth elements (REE), are essential modulators of microbial one-carbon metabolism. This chapter provides an overview of the gene expression study design and analysis protocols for uncovering REE-induced changes in methylotrophic bacteria. By interrogating relationships and differences in total gene
Zachary J, Johnson +3 more
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Genomic characterization of methylotrophy of Oharaeibacter diazotrophicus strain SM30T
Journal of Bioscience and Bioengineering, 2018Oharaeibacter diazotrophicus strain SM30T, isolated from rice rhizosphere, is an aerobic, facultative lanthanide (Ln3+)-utilizing methylotroph and diazotroph that belongs to the Methylocystaceae family. In this research, the complete genome sequence of strain SM30T was determined, and its methylotrophy modules were characterized. The genome consists of
Akio Tani
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Mycofactocin is essential for the establishment of methylotrophy in Mycobacterium smegmatis
Biochemical and Biophysical Research Communications, 2019Mycobacterium smegmatis possesses (N,N-dimethyl-4-nitrosoaniline)-dependent (NDMA) methanol dehydrogenase (Mno) to establish methylotrophy by utilizing methanol as the source of both carbon and energy. In this study, we show that Mno forms decamer and has NADPH as the bound cofactor. Interestingly, Mno uses NDMA and not NADP+ as an electron acceptor in
Abhishek Anil Dubey, Vikas Jain
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A novel Delftia plant symbiont capable of autotrophic methylotrophy
Microbiology, 2017A facultative methylotrophic bacterium, strain Lp-1, which was isolated from root nodules of lupine (Lupinus polyphyllus L.) on the medium with methanol as a carbon and energy source, exhibited high similarity of the 16S rRNA gene sequences to Delftia strains (94‒99.9%). The cells of Delftia sp.
N V, Agafonova +7 more
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