Results 1 to 10 of about 399 (130)
Unravelling Formaldehyde Metabolism in Bacteria: Road towards Synthetic Methylotrophy [PDF]
Microorganisms, 2022 Formaldehyde metabolism is prevalent in all organisms, where the accumulation of formaldehyde can be prevented through the activity of dissimilation pathways.
Vivien Jessica Klein +4 more
doaj +10 more sources
Methanol Dehydrogenases as a Key Biocatalysts for Synthetic Methylotrophy [PDF]
Frontiers in Bioengineering and Biotechnology, 2021 One-carbon (C1) chemicals are potential building blocks for cheap and sustainable re-sources such as methane, methanol, formaldehyde, formate, carbon monoxide, and more.
Thien-Kim Le +5 more
doaj +6 more sources
Synthetic C1 metabolism in Pseudomonas putida enables strict formatotrophy and methylotrophy via the reductive glycine pathway [PDF]
mBioFormate and methanol are promising alternatives to sugar-based feedstocks for biotechnological applications. These one-carbon (C1) substrates can be sustainably produced from CO2 and renewable electricity and assimilated by both native and engineered ...
Justine Turlin +5 more
doaj +7 more sources
Synthetic Methylotrophy in Yeasts: Towards a Circular Bioeconomy [PDF]
Trends in Biotechnology, 2021 Mitigating climate change is a key driver for the development of sustainable and CO2-neutral production processes. In this regard, connecting carbon capture and utilization processes to derive microbial C1 fermentation substrates from CO2 is highly promising. This strategy uses methylotrophic microbes to unlock next-generation processes, converting CO2-
Arne Roth, Volker Sieber
exaly +5 more sources
Synthetic Methylotrophy: Past, Present, and Future
, 2018 Methane and methanol are regarded as alternative and highly attractive nonfood raw materials for the biotechnology sector. The supply of methane and methanol comes from both fossil and renewable resources, rendering them flexible and sustainable raw materials. Reduced one-carbon (C1) compounds are used by specialized groups of microorganisms, i.e., the
Stephanie Heux +2 more
exaly +5 more sources
Identification of overoxidizing and non-overoxidizing NAD-dependent methanol dehydrogenases and implications for synthetic methylotrophy [PDF]
Nature CommunicationsSynthetic methylotrophy offers opportunities for sustainable chemical and biofuel production. While recently established methylotrophic E. coli can grow on methanol, undesirable formate accumulation occurs during growth and bioproduction.
Philipp Keller +10 more
doaj +4 more sources
Guidance for engineering of synthetic methylotrophy based on methanol metabolism in methylotrophy
RSC Advances, 2017 Methanol represents an attractive non-food raw material in biotechnological processes from an economic and process point of view. It is vital to elucidate methanol metabolic pathways, which will help to genetically construct non-native methylotrophs.
Wenming Zhang +2 more
exaly +3 more sources
Synthetic methylotrophy: Strategies to assimilate methanol for growth and chemicals production
Current Opinion in Biotechnology, 2019 Methanol is an attractive and broadly available substrate for large-scale bioproduction of fuels and chemicals. It contains more energy and electrons per carbon than carbohydrates and can be cheaply produced from natural gas. Synthetic methylotrophy refers to the development of non-native methylotrophs such as Escherichia coli and Corynebacterium ...
Maciek R Antoniewicz
exaly +4 more sources
Current Opinion in Biotechnology, 2015 Synthetic methylotrophy is the development of non-native methylotrophs that can utilize methane and methanol as sole carbon and energy sources or as co-substrates with carbohydrates to produce metabolites as biofuels and chemicals. The availability of methane (from natural gas) and its oxidation product, methanol, has been increasing, while prices have
Nicholas R Sandoval +2 more
exaly +4 more sources
Frontiers in Microbiology, 2021 There is great interest in developing synthetic methylotrophs that harbor methane and methanol utilization pathways in heterologous hosts such as Escherichia coli for industrial bioconversion of one-carbon compounds.
R. Kyle Bennett +8 more
doaj +1 more source