Results 11 to 20 of about 334 (106)

Toward Methanol-Based Biomanufacturing: Emerging Strategies for Engineering Synthetic Methylotrophy in Saccharomyces cerevisiae. [PDF]

open access: yesACS Synth Biol, 2022
The global expansion of biomanufacturing is currently limited by the availability of sugar-based microbial feedstocks, which require farmland for cultivation and therefore cannot support large increases in production without impacting the human food supply.
Kelso PA   +4 more
europepmc   +3 more sources

Rare earth elements in biology: From biochemical curiosity to solutions for extractive industries. [PDF]

open access: yesMicrob Biotechnol
To meet society's demands for technologies that use rare earth elements (including those that allow a decarbonized society), we need to increase the volume and efficiency of extraction by mining and recycling. Microbial rare earth biochemistry offers numerous enabling biotechnologies to achieve this. Abstract Rare earth elements (REEs) are critical for
Rocha RA, Alexandrov K, Scott C.
europepmc   +2 more sources

The cofactor challenge in synthetic methylotrophy: bioengineering and industrial applications

open access: yesCurrent Opinion in Biotechnology, 2023
Methanol is a promising feedstock for industrial bioproduction: it can be produced renewably and has high solubility and limited microbial toxicity. One of the key challenges for its bio-industrial application is the first enzymatic oxidation step to formaldehyde.
Krüsemann, Jan L.   +4 more
openaire   +4 more sources

Non-natural Aldol Reactions Enable the Design and Construction of Novel One-Carbon Assimilation Pathways in vitro

open access: yesFrontiers in Microbiology, 2021
Methylotrophs utilizes cheap, abundant one-carbon compounds, offering a promising green, sustainable and economical alternative to current sugar-based biomanufacturing.
Yufeng Mao   +15 more
doaj   +1 more source

Cross-Feeding of a Toxic Metabolite in a Synthetic Lignocellulose-Degrading Microbial Community

open access: yesMicroorganisms, 2021
The recalcitrance of complex organic polymers such as lignocellulose is one of the major obstacles to sustainable energy production from plant biomass, and the generation of toxic intermediates can negatively impact the efficiency of microbial ...
Jessica A. Lee   +5 more
doaj   +1 more source

Lanthanide-Controlled Protein Switches: Development and In Vitro and In Vivo Applications. [PDF]

open access: yesAngew Chem Int Ed Engl
Engineering artificial allosteric protein switches controlled by rare earth elements allows the development of assays, construction of bioelectronic devices, and REE‐controlled microorganisms. Abstract Lanthanides, which are part of the rare earth elements group have numerous applications in electronics, medicine and energy storage.
Guo Z   +9 more
europepmc   +3 more sources

Responses to organic pollutants in the tropical Pacific and subtropical Atlantic Oceans by pelagic marine bacteria

open access: yesFrontiers in Environmental Science, 2023
Background and chronic pollution by organic pollutants (OPs) is a widespread threat in the oceans with still uncharacterized effects on marine ecosystems and the modulation of major biogeochemical cycles.
Maria Vila-Costa   +7 more
doaj   +1 more source

Core and auxiliary functions of one-carbon metabolism in Pseudomonas putida exposed by a systems-level analysis of transcriptional and physiological responses

open access: yesmSystems, 2023
The soil bacterium Pseudomonas putida is a robust biomanufacturing host that assimilates a broad range of substrates while efficiently coping with adverse environmental conditions. P. putida is equipped with functions related to one-carbon (C1) compounds
Justine Turlin   +4 more
doaj   +1 more source

Discovery and Biochemical Characterization of a Methanol Dehydrogenase From Lysinibacillus xylanilyticus

open access: yesFrontiers in Bioengineering and Biotechnology, 2020
Bioconversion of C1 chemicals such as methane and methanol into higher carbon-chain chemicals has been widely studied. Methanol oxidation catalyzed by methanol dehydrogenase (Mdh) is one of the key steps in methanol utilization in bacterial methylotrophy.
Jin-Young Lee   +19 more
doaj   +1 more source

Paleometagenomics reveals environmental microbiome response to vegetation changes in northern Siberia over the millennia

open access: yesEnvironmental DNA, Volume 5, Issue 6, Page 1252-1264, November 2023., 2023
We integrated taxonomic with functional gene analysis, which enabled to shed light not only on community compositions but also on long‐term eco‐physiological adaptations and ecosystem functioning. Various genes coding enzymes responsible for biomass degradation, carbon metabolism, and adaptation to environmental stress were identified and traced over ...
Amedea Perfumo   +6 more
wiley   +1 more source

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