Results 31 to 40 of about 399 (130)

Core and auxiliary functions of one-carbon metabolism in Pseudomonas putida exposed by a systems-level analysis of transcriptional and physiological responses

mSystems, 2023
The soil bacterium Pseudomonas putida is a robust biomanufacturing host that assimilates a broad range of substrates while efficiently coping with adverse environmental conditions. P. putida is equipped with functions related to one-carbon (C1) compounds
Justine Turlin, Òscar Puiggené, Stefano Donati, Nicolas T. Wirth, Pablo I. Nikel   +4 more
doaj   +1 more source

Paleometagenomics reveals environmental microbiome response to vegetation changes in northern Siberia over the millennia

Environmental DNA, Volume 5, Issue 6, Page 1252-1264, November 2023., 2023
We integrated taxonomic with functional gene analysis, which enabled to shed light not only on community compositions but also on long‐term eco‐physiological adaptations and ecosystem functioning. Various genes coding enzymes responsible for biomass degradation, carbon metabolism, and adaptation to environmental stress were identified and traced over ...
Amedea Perfumo, Uğur Çabuk, Luise Schulte, Jérémy Courtin, Lars Harms, Kathleen R. Stoof‐Leichsenring, Ulrike Herzschuh   +6 more
wiley   +1 more source

Improved succinic acid production through the reconstruction of methanol dissimilation in Escherichia coli

Bioresources and Bioprocessing, 2022
Synthetic biology has boosted the rapid development on using non-methylotrophy as chassis for value added chemicals production from one-carbon feedstocks, such as methanol and formic acid.
Feng Guo, Min Wu, Shangjie Zhang, Yifan Feng, Yujia Jiang, Wankui Jiang, Fengxue Xin, Wenming Zhang, Min Jiang   +8 more
doaj   +1 more source

Adaptive genetic traits in pelagic freshwater microbes

Environmental Microbiology, Volume 25, Issue 3, Page 606-641, March 2023., 2023
Abstract Pelagic microbes have adopted distinct strategies to inhabit the pelagial of lakes and oceans and can be broadly categorized in two groups: free‐living, specialized oligotrophs and patch‐associated generalists or copiotrophs. In this review, we aim to identify genomic traits that enable pelagic freshwater microbes to thrive in their habitat ...
Maria‐Cecilia Chiriac, Markus Haber, Michaela M. Salcher   +2 more
wiley   +1 more source

Synthetic methylotrophy: Engineering microbes for sustainable biomanufacturing from C1 compounds

Systems Microbiology and Biomanufacturing
Vaibhav Vinod Phokmare, Satish Chandra Pandey, Prashant Khare   +2 more
exaly   +2 more sources

Leveraging substrate flexibility and product selectivity of acetogens in two‐stage systems for chemical production

Microbial Biotechnology, Volume 16, Issue 2, Page 218-237, February 2023., 2023
Carbon dioxide recycling is a compelling need and microbial carbon dioxide fixation in value‐added compounds is a valuable opportunity. Fermentation of CO2 gas streams using acetogenic bacteria is consolidating as a key biotechnology to move toward a cyclic carbon economy.
Luca Ricci, Arne Seifert, Sebastien Bernacchi, Debora Fino, Candido Fabrizio Pirri, Angela Re   +5 more
wiley   +1 more source

Natural Selection in Synthetic Communities Highlights the Roles of Methylococcaceae and Methylophilaceae and Suggests Differential Roles for Alternative Methanol Dehydrogenases in Methane Consumption

Frontiers in Microbiology, 2017
We describe experiments that follow species dynamics and gene expression patterns in synthetic bacterial communities including species that compete for the single carbon substrate supplied, methane, and species unable to consume methane, which could only
Zheng Yu, David A. C. Beck, David A. C. Beck, Ludmila Chistoserdova   +3 more
doaj   +1 more source

Methanol production by reversed methylotrophy constructed in Escherichia coli

, 2020
We constructed a reversed methylotrophic pathway that produces methanol, a promising feedstock for production of useful compounds, from fructose 6-phosphate (F6P), which can be supplied by catabolism of biomass-derived sugars including glucose, by a ...
Miyabi Yamakita (8310828), Kento Fujisawa (8310831), Yasuyoshi Sakai (203875), Tomoyuki Takeya (8310825), Daisuke Hayashi (387198), Hiroya Yurimoto (203873)   +5 more
core   +1 more source

Regulatory interventions improve the biosynthesis of limiting amino acids from methanol carbon to improve synthetic methylotrophy in Escherichia coli

Biotechnology and Bioengineering, 2020
AbstractSynthetic methylotrophy aims to engineer methane and methanol utilization pathways in platform hosts like Escherichia coli for industrial bioprocessing of natural gas and biogas. While recent attempts to engineer synthetic methylotrophs have proved successful, autonomous methylotrophy, that is, the ability to utilize methane or methanol as sole
Robert Kyle Bennett, Alec Agee, Jie R. G. Har, Bryan von Hagel, Maciek R. Antoniewicz, Eleftherios T. Papoutsakis   +5 more
openaire   +3 more sources

Engineering Yeast Yarrowia lipolytica for Methanol Assimilation

, 2021
Conferring methylotrophy on industrial microorganisms would enable the production of diverse products from one-carbon feedstocks and contribute to establishing a low-carbon society.
Olofsson-Dolk, Mattis, Hansson, Frederik Gleerup, Chang, Hong, Cheng, Jian, Donati, Stefano, Li, Xiaolin, Wang, Guokun, Borodina, Irina, Dahlin, Jonathan   +8 more
core   +1 more source