The effects of joint aspiration and intra-articular corticosteroid injection on flexion reflex excitability, quadriceps strength and pain in individuals with knee synovitis: a prospective observational study [PDF]
Substantial weakness of the quadriceps muscles is typically observed in patients with arthritis. This is partly due to ongoing neural inhibition that prevents the quadriceps from being fully activated.
Dalbeth, N +3 more
core +2 more sources
ABSTRACT Background Inadequate postoperative pain management after lumbar discectomy may delay recovery, increase the risk of chronic pain, and prolong hospitalization. Effective analgesic strategies must balance pain control with minimal adverse effects.
Josephine Zachodnik +7 more
wiley +1 more source
Abstract Glucocorticoids (GCs) are widely utilised for the treatment of inflammatory and autoimmune conditions but often precipitate significant hyperglycaemia. People with type 1 diabetes (PWT1D) may be particularly affected due to the challenges of adjusting insulin dosing, for which recommendations remain unclear.
Alexandra Katz +8 more
wiley +1 more source
ABSTRACT Background Plantar fasciitis (PF) is a common cause of heel pain that affects the health‐related quality of life of many individuals and has various treatment options. Two effective interventions are corticosteroid (CS) injections and dextrose prolotherapy (DP).
Ruaa Mustafa Qafesha +4 more
wiley +1 more source
Long‐Term Outcomes of Prepubertal‐Onset Vulvar Lichen Sclerosus
ABSTRACT Background Vulvar lichen sclerosus (VLS) is a chronic inflammatory dermatosis affecting the vulvar and perianal skin. VLS has a bimodal age of onset, in pre‐pubertal and post‐menopausal age groups. Long‐term outcomes of pre‐pubertal VLS are unclear.
Alexandra Savage +5 more
wiley +1 more source
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo +11 more
wiley +1 more source
Feasibility randomised multicentre, double-blind, double-dummy controlled trial of anakinra, an interleukin-1 receptor antagonist versus intramuscular methylprednisolone for acute gout attacks in patients with chronic kidney disease (ASGARD): protocol study [PDF]
Introduction: Acute gout occurs in people with chronic kidney disease, who are commonly older people with comorbidities such as hypertension, heart disease and diabetes.
Ahmed, Khalid +14 more
core +2 more sources
Ultrasound‐guided, minimally invasive, biceps brachii tenotomy in a standing horse
Abstract Objective To describe the long‐term outcome of a horse that underwent a standing, ultrasound‐guided, minimally invasive, biceps brachii tenotomy. Study design Case report. Animal A 17‐year‐old Tennessee Walking Horse gelding. Methods The horse had a chronic, severe, lameness localized to the left shoulder region.
Guilherme F. Marques +4 more
wiley +1 more source
Assessment of Pain Types in Recently Diagnosed Patients With Inflammatory Arthritis
Objective Up to 40% of patients with inflammatory arthritis (IA) experience persistent pain, traditionally thought to be associated with a shift from peripherally to centrally mediated pain during the disease course in some patients. We assessed sensory profiles of recently diagnosed individuals with IA, hypothesizing that pain reported at this early ...
Zoe Rutter‐Locher +8 more
wiley +1 more source
Steroid induced osteonecrosis: An analysis of steroid dosing risk. [PDF]
Osteonecrosis is a serious condition involving bone destruction that frequently requires surgical treatment to rebuild the joint. While there is an abundance of literature documenting corticosteroid related osteonecrosis, there is no consensus as to the ...
Chang, Christopher +4 more
core +1 more source

