Results 131 to 140 of about 64,774 (259)

Biosynthese des vollständig gesättigten C16‐Homosesquiterpens Descartan durch Deprotonierung mit Cyclopropanierung

open access: yesAngewandte Chemie, EarlyView.
Eine nicht‐kanonische C16‐Sesquiterpensynthase aus Morganella morganii produziert das ungewöhnliche Grundgerüst Descartan. Ihr Cyclisierungsmechanismus wurde mittels Isotopenmarkierungsexperimenten und DFT‐Berechnungen aufgeklärt. Gezielte Mutagenese veränderte die Enzymfunktion und führte zu alternativen Produkten, darunter Voltairen, dessen ...
Kexin Yang   +4 more
wiley   +1 more source

Histone Methylation: A Pivotal Epigenetic Driver of the Malignant Transformation of MASLD-HCC. [PDF]

open access: yesJ Hepatocell Carcinoma
Zhang Y   +9 more
europepmc   +1 more source

Biosynthesis of the Fully Saturated C16 Homosesquiterpene Descartane Through Deprotonation With Cyclopropanation

open access: yesAngewandte Chemie International Edition, EarlyView.
A non‐canonical C16 sesquiterpene synthase from Morganella morganii produces the unusual scaffold descartane. Its cyclisation mechanism was rationalised by isotopic labelling experiments and DFT calculations. Site‐directed mutagenesis altered enzyme function, resulting in alternative products, including voltairene, which requires a different ...
Kexin Yang   +4 more
wiley   +1 more source

Meeting report on FASEB protein arginine methylation: mechanism to therapeutics. [PDF]

open access: yesJ Biol Chem
Shechter D   +22 more
europepmc   +1 more source

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