Results 1 to 10 of about 58,830 (269)

EFFECT OF METOPROLOL ON COGNITIVE FUNCTION IN HYPERTENSIVE PATIENTS OF YOUNG TO MIDDLE AGE

open access: diamondРациональная фармакотерапия в кардиологии, 2016
Aim. To evaluate the effect of metoprolol tartrate on blood pressure (BP) and cognitive function in young to middle aged patients with essential hypertension (HT).Material and methods.
S. A. Smakotina   +2 more
doaj   +3 more sources

Effectiveness of Metoprolol in Improving Cardiac and Motor Functions in Patients with Chronic Heart Failure: A Prospective Study

open access: goldDrug Design, Development and Therapy, 2020
XiaoLiang Cheng,1 Min Zhu,2 Qing Liu,3 Zhenxia Feng,2 Yong Meng2 1Department of Endocrinology, The Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, People’s Republic of China; 2Department of Cardiology, The Second ...
Cheng X, Zhu M, Liu Q, Feng Z, Meng Y
doaj   +1 more source

Baseline Corrected QT Interval Dispersion Is Useful to Predict Effectiveness of Metoprolol on Pediatric Postural Tachycardia Syndrome

open access: yesFrontiers in Cardiovascular Medicine, 2022
ObjectivesThe study was designed to explore the role of baseline-corrected QT interval dispersion (QTcd) in predicting the effectiveness of metoprolol on pediatric postural tachycardia syndrome (POTS).MethodsThere were two groups in the study, the ...
Yuanyuan Wang   +10 more
doaj   +1 more source

Effects of pre-treatment with metoprolol and diltiazem on cerebral ischemia/reperfusion-induced injuries

open access: yesBrazilian Journal of Pharmaceutical Sciences, 2023
Stroke is one of the most important health concerns worldwide. Calcium ions accumulation in the nerve cells and increase in the catecholamines level of the brain following cerebral ischemia/reperfusion (I/R) are accompanied by damaging effects. Therefore,
Ghazaleh Sadrhaghighi   +4 more
doaj   +1 more source

Metoprolol rescues endothelial progenitor cell dysfunction in diabetes [PDF]

open access: yesPeerJ, 2020
Added risk portended by diabetes in addition to hypertension has been related to an amplification of endothelial dysfunction. β-blockers are widely used for cardiovascular diseases and improve the endothelial function compared with a placebo.
Lang Yan   +12 more
doaj   +2 more sources

Metabolomic profiling of metoprolol hypertension treatment reveals altered gut microbiota-derived urinary metabolites

open access: yesHuman Genomics, 2020
Introduction Metoprolol succinate is a long-acting beta-blocker prescribed for the management of hypertension (HTN) and other cardiovascular diseases.
Chad N. Brocker   +9 more
doaj   +1 more source

Impact of amiodarone use on metoprolol concentrations, α‐OH‐metoprolol concentrations, metoprolol dosing and heart rate: A cross‐sectional study

open access: yesPharmacology Research & Perspectives, 2023
Small studies suggest that amiodarone is a weak inhibitor of cytochrome P450 (CYP) 2D6. Inhibition of CYP2D6 leads to increases in concentrations of drugs metabolized by the enzyme, such as metoprolol. Considering that both metoprolol and amiodarone have
Sabrina Robert   +11 more
doaj   +1 more source

Leveraging large observational studies to discover genetic determinants of drug concentrations: A proof‐of‐concept study

open access: yesClinical and Translational Science, 2022
Large, observational genetic studies are commonly used to identify genetic factors associated with diseases and disease‐related traits. Such cohorts have not been commonly used to identify genetic predictors of drug dosing or concentrations, perhaps ...
Maxime Meloche   +9 more
doaj   +1 more source

Quercetin declines plasma exposure of metoprolol tartrate in the rat model

open access: yesJournal of Advanced Pharmaceutical Technology & Research, 2014
The study was undertaken to evaluate the effect of quercetin on the pharmacokinetics of Metoprolol tartrate. A single dose in vivo pharmacokinetic study was carried out in rat models.
Siva R Challa   +2 more
doaj   +1 more source

Green spectrofluorimetric quantification of aspirin, olmesartan, and metoprolol in spiked human plasma

open access: yesScientific Reports, 2023
Low dose aspirin is routinely taken with antihypertensive drugs such as olmesartan and metoprolol to avoid the cardiovascular and renal outcomes associated with high blood pressure. The first spectrofluorimetric method for quantifying aspirin, olmesartan,
Ali Alqahtani   +3 more
doaj   +1 more source

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