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EFFECT OF METOPROLOL ON COGNITIVE FUNCTION IN HYPERTENSIVE PATIENTS OF YOUNG TO MIDDLE AGE
Aim. To evaluate the effect of metoprolol tartrate on blood pressure (BP) and cognitive function in young to middle aged patients with essential hypertension (HT).Material and methods.
S. A. Smakotina +2 more
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XiaoLiang Cheng,1 Min Zhu,2 Qing Liu,3 Zhenxia Feng,2 Yong Meng2 1Department of Endocrinology, The Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, People’s Republic of China; 2Department of Cardiology, The Second ...
Cheng X, Zhu M, Liu Q, Feng Z, Meng Y
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ObjectivesThe study was designed to explore the role of baseline-corrected QT interval dispersion (QTcd) in predicting the effectiveness of metoprolol on pediatric postural tachycardia syndrome (POTS).MethodsThere were two groups in the study, the ...
Yuanyuan Wang +10 more
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Stroke is one of the most important health concerns worldwide. Calcium ions accumulation in the nerve cells and increase in the catecholamines level of the brain following cerebral ischemia/reperfusion (I/R) are accompanied by damaging effects. Therefore,
Ghazaleh Sadrhaghighi +4 more
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Metoprolol rescues endothelial progenitor cell dysfunction in diabetes [PDF]
Added risk portended by diabetes in addition to hypertension has been related to an amplification of endothelial dysfunction. β-blockers are widely used for cardiovascular diseases and improve the endothelial function compared with a placebo.
Lang Yan +12 more
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Introduction Metoprolol succinate is a long-acting beta-blocker prescribed for the management of hypertension (HTN) and other cardiovascular diseases.
Chad N. Brocker +9 more
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Small studies suggest that amiodarone is a weak inhibitor of cytochrome P450 (CYP) 2D6. Inhibition of CYP2D6 leads to increases in concentrations of drugs metabolized by the enzyme, such as metoprolol. Considering that both metoprolol and amiodarone have
Sabrina Robert +11 more
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Large, observational genetic studies are commonly used to identify genetic factors associated with diseases and disease‐related traits. Such cohorts have not been commonly used to identify genetic predictors of drug dosing or concentrations, perhaps ...
Maxime Meloche +9 more
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Quercetin declines plasma exposure of metoprolol tartrate in the rat model
The study was undertaken to evaluate the effect of quercetin on the pharmacokinetics of Metoprolol tartrate. A single dose in vivo pharmacokinetic study was carried out in rat models.
Siva R Challa +2 more
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Low dose aspirin is routinely taken with antihypertensive drugs such as olmesartan and metoprolol to avoid the cardiovascular and renal outcomes associated with high blood pressure. The first spectrofluorimetric method for quantifying aspirin, olmesartan,
Ali Alqahtani +3 more
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