Results 71 to 80 of about 58,830 (269)

Development of a sensitive and rapid method for quantitation of (S)-(−)- and (R)-(+)-metoprolol in human plasma by chiral LC–ESI–MS/MS

open access: yesJournal of Pharmaceutical Analysis, 2014
A selective, sensitive and high throughput liquid chromatography-tandem mass spectrometry (LC–ESI–MS/MS) method has been developed for separation and quantification of metoprolol enantiomers on a chiral Lux Amylose-2 (250mm×4.6mm, 5μm) column ...
Primal Sharma   +4 more
doaj   +1 more source

Metoprolol and atenolol in mild-to-moderate chronic heart failure: The comparison of survival benefit [PDF]

open access: yesSrpski Arhiv za Celokupno Lekarstvo, 2005
The clinical end-point of all causes of mortality and cardiovascular hospitalization (combined end-points) is a widely accepted indicator of heart failure survival.
Ćelić Vera   +4 more
doaj   +1 more source

Present and future pharmacotherapeutic agents in heart failure: an evolving paradigm [PDF]

open access: yes, 2016
Many conditions culminate in heart failure (HF), a multi-organ systemic syndrome with an intrinsically poor prognosis. Pharmacotherapeutic agents that correct neurohormonal dysregulation and haemodynamic instability have occupied the forefront of ...
Abozguia   +119 more
core   +1 more source

First Report on Atrial Leadless Pacing in a Lateral Tunnel Fontan Patient

open access: yesJournal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Introduction No reports on atrial leadless pacing have been demonstrated in patients with the Fontan palliation. We present the case of a patient with a Lateral tunnel Fontan palliation with leadless pacing system for symptomatic bradycardia in the setting of sinus node dysfunction. Methods After internal review board approval, a retrospective
Daniel Cortez   +2 more
wiley   +1 more source

ER/K linked GPCR-G protein fusions systematically modulate second messenger response in cells. [PDF]

open access: yes, 2017
FRET and BRET approaches are well established for detecting ligand induced GPCR-G protein interactions in cells. Currently, FRET/BRET assays rely on co-expression of GPCR and G protein, and hence depend on the stoichiometry and expression levels of the ...
Dysthe, Matthew   +4 more
core   +1 more source

The Swedish CArdioPulmonary bioImage Study re‐examination: Rationale, design, methods, and management of incidental findings

open access: yesJournal of Internal Medicine, EarlyView.
Abstract Objectives To describe the rationale, design and data collection procedures of the Swedish CArdioPulmonary bioImage Study (SCAPIS) re‐examination, which, in its further scope, aims to quantify and explain the development of atherosclerosis, pathological cardiovascular ageing, longitudinal decline in lung function and the malignant ...
Elin Good   +21 more
wiley   +1 more source

Metoprolol Dose Equivalence in Adult Men and Women Based on Gender Differences: Pharmacokinetic Modeling and Simulations

open access: yesMedical Sciences, 2016
Recent meta-analyses and publications over the past 15 years have provided evidence showing there are considerable gender differences in the pharmacokinetics of metoprolol.
Andy R. Eugene
doaj   +1 more source

Parasomnias and sleep‐related movement disorders induced by drugs in the adult population: a review about iatrogenic medication effects

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Parasomnias and sleep‐related movement disorders (SRMD) are major causes of sleep disorders and may be drug induced. The objective of this study was to conduct a systematic review of the literature to examine the association between drug use and the occurrence of parasomnias and SRMD.
Sylvain Dumont   +5 more
wiley   +1 more source

Metoprolol use is associated with improved outcomes in patients with sepsis-induced cardiomyopathy: an analysis of the MIMIC-IV database

open access: yesBMC Cardiovascular Disorders
Background Metoprolol is commonly administered to critically ill patients; however, its effect on mortality in patients with sepsis-induced cardiomyopathy (SICM) remains uncertain.
Liping Zhong   +3 more
doaj   +1 more source

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