Results 81 to 90 of about 58,830 (269)

Bioanalytical method development and validation for determination of metoprolol tartarate and hydrochlorothiazide using HPTLC in human plasma

open access: yesBrazilian Journal of Pharmaceutical Sciences, 2013
A simple, sensitive, rapid and economic chromatographic method has been developed for determination of metoprolol tartarate and hydrochlorothiazide in human plasma using paracetamol as an internal standard.
Ambadas Ranganath Rote   +1 more
doaj   +1 more source

Melt-extruded polyethylene oxide (PEO) rods as drug delivery vehicles: Formulation, performance as controlled release devices and the influence of co-extruded excipients on drug release profiles [PDF]

open access: yes, 2012
The utility of controlled release medication formulations lies in their ability to keep drugs at steady levels in the blood plasma of recipients and within the termini of the maximum and minimum effective therapeutic levels.
Mucalo, Michael R., Rathbone, Michael J.
core   +1 more source

Dreaming conundrum

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Dreaming, a common yet mysterious cognitive phenomenon, is an involuntary process experienced by individuals during sleep. Although the fascination with dreams dates back to ancient times and gained therapeutic significance through psychoanalysis in the early twentieth century, its scientific investigation only gained momentum with the ...
Carlotta Mutti   +2 more
wiley   +1 more source

What is the most effective beta-blocker for heart failure? [PDF]

open access: yes, 2003
Three beta-blockers--carvedilol, metoprolol, and bisoprolol--reduce mortality in chronic heart failure caused by left ventricular systolic dysfunction, when used in addition to diuretics and angiotensin converting enzyme (ACE) inhibitors (strength of ...
Neher, Jon O., Safranek, Sarah
core  

Effects of different degrees of sympathetic antagonism on cytokine network in patients with ischemic dilated cardiomyopathy [PDF]

open access: yes, 2005
BACKGROUND: The proinflammatory cytokines have been implicated in the pathogenesis of heart failure. Recent studies have shown that beta-adrenergic blockade can modulate cytokine production.
Cinquegrana, G.   +7 more
core   +1 more source

Sleep characteristics and self‐reported sleep quality in the oldest‐old: Results from a prospective longitudinal cohort study

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Little is known about the correlation between subjective perception and objective measures of sleep quality in particular in the oldest‐old. The aim of this study was to perform longitudinal home sleep monitoring in this age group, and to correlate results with self‐reported sleep quality.
Hugo Saner   +4 more
wiley   +1 more source

Methods of Assessment and Clinical Relevance of QT Dynamics [PDF]

open access: yes, 2005
The dependence on heart rate of the QT interval has been investigated for many years and several mathematical formulae have been proposed to describe the QT interval/heart rate (or QT interval/RR interval) relationship. While the most popular is Bazett’s
Agata, Musialik-Lydka   +4 more
core  

Behavioral-Independent Features of Complex Heartbeat Dynamics [PDF]

open access: yes, 2001
We test whether the complexity of cardiac interbeat interval time series is simply a consequence of the wide range of scales characterizing human behavior, especially physical activity, by analyzing data taken from healthy adult subjects under three ...
Amaral, Luis A. Nunes   +7 more
core   +1 more source

Clinical guidelines highlight for the hospitalist: Management of cyclic vomiting syndrome in children

open access: yes
Journal of Hospital Medicine, EarlyView.
Yamileth N. Hernandez, Hannah M. Gardner
wiley   +1 more source

Transforming Treatment: The Impact of Bariatric Surgery on Oral Drug Absorption

open access: yesObesity Reviews, EarlyView.
ABSTRACT Obesity represents a significant threat to global public health, with an estimated 16% of adults worldwide (2022) being classified as people with obesity, with a body mass index of 30 or more. Bariatric surgery is regarded as the most effective treatment option for people with obesity, with the three main types of bariatric surgery being ...
Danielle Wigg   +3 more
wiley   +1 more source

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