Results 101 to 110 of about 31,613 (220)

Metoprolol succinate (CR/XL): Advanced formulation of classical b-blocker

open access: yes, 2020
Metoprolol is a selective beta(1)-adrenergic antagonist extensively used in major fields of cardiology since 1975. Metoprolol has proven its efficacy in reducing cardiovascular events and mortality in patients with hypertension and coronary heart disease
Gudkov K.M., Kobalava Z.D.
core  

Effects of Celecoxib and Etoricoxib on the Pharmacokinetics and Pharmacological Effects of Orally Administered Tramadol: A Randomised Controlled Trial

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 139, Issue 1, July 2026.
ABSTRACT Tramadol is a widely used analgesic whose bioactivation to O‐desmethyltramadol is primarily mediated by cytochrome P450 2D6 (CYP2D6). Genetic variability and drug–drug interactions affecting CYP2D6 may influence tramadol pharmacokinetics and pharmacological effects.
Tuukka Saarikoski   +6 more
wiley   +1 more source

Graphene Oxide/Polyethylene Glycol-Stick for Thin Film Microextraction of β-Blockers from Human Oral Fluid by Liquid Chromatography-Tandem Mass Spectrometry

open access: yesMolecules, 2019
A wooden stick coated with a novel graphene-based nanocomposite (Graphene oxide/polyethylene glycol (GO/PEG)) is introduced and investigated for its efficacy in solid phase microextraction techniques.
Hanieh Karimiyan   +5 more
doaj   +1 more source

The use of metoprolol CR/XL in the treatment of patients with diabetes and chronic heart failure

open access: yes, 2006
Ovidio De Freitas, Oliver Lenz, Alessia Fornoni, Barry J MatersonDivision of Nephrology and Hypertension, Department of Medicine, Miller School of Medicine, University of Miami, Miami, Florida, USAAbstract: About 5 million Americans suffer from heart ...
Oliver Lenz   +7 more
core  

DMAP1 Deficiency Suppresses Lung Cancer Progression by Destabilizing Replication Fork and Activating IFN Signaling‐Mediated Anti‐tumor Immunity

open access: yesAdvanced Science, Volume 13, Issue 33, 15 June 2026.
Lung cancer remains the leading cause of cancer‐related death. We investigated the role of the epigenetic regulator DMAP1 in NSCLC and found that its loss induces replication stress and DNA damage. This in turn activates type I IFN signaling via the cGAS–STING pathway and transcriptional ISG de‐repression, enhancing anti‐tumor immune responses ...
Kan Huang   +10 more
wiley   +1 more source

Soft and Adhesive Cardiac Patch for Electrophysiological and Contraction Measurement

open access: yesAdvanced Science, Volume 13, Issue 34, 19 June 2026.
This study developed an epicardial electronic patch with a modulus similar to that of the heart (approximately 65kPa), which can collect stable electrocardiogram signals and myocardial contractility on the surface of a dynamically beating heart. This is attributed to the hydrogen bond interaction formed between the amino and catechol groups in the ...
Wuliang Chen   +10 more
wiley   +1 more source

Influence of pentobarbital on metoprolol plasma levels

open access: yes, 1979
Induction of microsomal enzymes with barbiturates in rats has little effect on the metabolism of metoprolol, compared with propranolol and alprenolol, which undergo extensive hepatic extraction in animals and man.
Borg, KO   +4 more
core   +1 more source

The Heart of the Thymus: A Rare Tale of Nonischemic Cardiomyopathy in the Absence of Myasthenia Gravis

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Thymomas are rare epithelial tumors of the anterior mediastinum known for their association with autoimmune and paraneoplastic syndromes, most notably myasthenia gravis (MG). Cardiomyopathy is an exceptionally rare paraneoplastic manifestation.
Manish Barman   +5 more
wiley   +1 more source

Percutaneous drug delivery of metoprolol.

open access: yes, 1996
Percutaneous drug delivery of ...
Meidong. Yang (7979162)
core  

Takotsubo Syndrome Mimicking Apical Hypertrophic Cardiomyopathy: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
Graphical abstract showing possible clinical findings in Takotsubo syndrome and apical hypertrophic cardiomyopathy. ABSTRACT Takotsubo syndrome (TTS) is a reversible form of cardiomyopathy that is triggered by emotional or physical stress, leading to a typical image of apical ballooning.
Benjamin Vögeli   +5 more
wiley   +1 more source

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