Results 71 to 80 of about 669,922 (254)

On The Local Metric Dimension of Line Graph of Special Graph

open access: yesCauchy: Jurnal Matematika Murni dan Aplikasi, 2016
Let G be a simple, nontrivial, and connected graph.  is a representation of an ordered set of k distinct vertices in a nontrivial connected graph G. The metric code of a vertex v, where , the ordered  of k-vector is representations of v with respect to W,
Marsidi Marsidi   +3 more
doaj   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

A study on Quantization Dimension in complete metric spaces [PDF]

open access: green, 2022
Mrinal Kanti Roychowdhury, Saurabh Verma
openalex   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

Fault-Tolerant Metric Dimension of Interconnection Networks

open access: yesIEEE Access, 2020
A fixed interconnection parallel architecture is characterized by a graph, with vertices corresponding to processing nodes and edges representing communication links.
Sakander Hayat   +4 more
doaj   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

DIMENSI METRIK PADA GRAF Rn(q; r)m

open access: yesJurnal Matematika UNAND, 2019
The metric dimension of a connected graph G is the cardinality of minimum resolving set in graph G. In this research, how to find the metric dimension of Rn(q; r)m graph. Rn(q; r)m graph is constructing by subdivision operation on Lobster graph Ln(q; r).
Rendy Aditya Pratama   +2 more
doaj   +1 more source

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